Sequencing of the MHC region defines HLA-DQA1 as the major genetic risk for seropositive rheumatoid arthritis in Han Chinese population - Guo, Jianping; Zhang, Tao; Cao, Hongzhi; Li, Xiaowei; Liang, Hao; Liu, Mengru; Zou, Yundong; Zhang, Yuanwei; Wang, Yuxuan; Sun, Xiaolin; Hu, Fanlei; Du, Yan; et al. (Annals of the rheumatic diseases, 2019)
Keywords: Adult; Aged; Amino acids; ant-ccp; Anti-Citrullinated Protein Antibodies - immunology; Antigens; Arginine; Arthritis, Rheumatoid - genetics; Arthritis, Rheumatoid - immunology; Asian People - genetics; Case-Control Studies; Cell activation; Dermatology; DQA1 protein; Drb1 protein; Female; Gene mapping; gene polymorphism; Genes; Genetic Predisposition to Disease; Genomes; Genomics; Genotyping; Haplotypes; High-Throughput Nucleotide Sequencing - methods; Histocompatibility antigen HLA; Histocompatibility Testing - methods; HLA-DQ alpha-Chains - genetics; HLA-DRB1 Chains - genetics; Hospitals; Humans; Immunoglobulins; Immunology; Linkage disequilibrium; Lymphocyte Activation - genetics; Lymphocytes; Lymphocytes T; Major histocompatibility complex; Male; Middle Aged; Peptides; Polymorphism; Population genetics; Proteins; Rheumatoid arthritis; Rheumatology; T-Lymphocytes - immunology; Tissue typing; Beijing China; Sweden; China; ant-ccp; gene polymorphism; rheumatoid arthritis