Transcriptional sexual dimorphism in elongating bovine embryos: implications for XCI and sex determination genes

• Published in: Reproduction (Cambridge, England) Vol. 141; no. 6; pp. 801 - 808
• Main Authors: Bermejo-Alvarez, P, Rizos, D, Lonergan, P, Gutierrez-Adan, A
• Format: Journal Article
• Language: English
• Published: England BioScientifica 01.06.2011; BioScientifica Ltd; Society for Reproduction and Fertility
• Subjects: Analysis of Variance; Animals; blastocyst; Blastocyst - physiology; calpain; Cattle; Embryo Culture Techniques; Embryonic Development; embryonic mortality; evolution; Female; females; Fertilization in Vitro; gene expression regulation; Gene Expression Regulation, Developmental; genes; Genes, X-Linked; Gestational Age; glucose-6-phosphate 1-dehydrogenase; glutathione transferase; hatching; interferons; laminin; Male; males; progesterone receptors; Sex Characteristics; sex determination; Sex Determination Analysis; Sex Determination Processes - genetics; sex hormones; sexual dimorphism; spermidine; spermine; transcription (genetics); Transcription, Genetic; ubiquitin-protein ligase; X Chromosome; X Chromosome Inactivation; zinc finger motif

Sex chromosome transcripts can lead to a broad transcriptional sexual dimorphism in the absence of concomitant or previous exposure to sex hormones, especially when X-chromosome inactivation (XCI) is not complete. XCI timing has been suggested to differ greatly among species, and in bovine, most of...