Using microfluidic shear to assess transfusion requirements in trauma patients

• Published in: Trauma surgery & acute care open Vol. 9; no. 1; p. e001403
• Main Authors: Vuoncino, Leslie H, Robles, Anamaria J, Barnes, Ashli C, Ross, James T, Graeff, Leonardo W, Anway, Taylor L, Vincent, Nico T, Tippireddy, Nithya, Tanaka, Kimi M, Mays, Randi J, Callcut, Rachael A
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group Ltd 05.07.2024; BMJ Publishing Group LTD; BMJ Publishing Group
• Subjects: Blood coagulation; blood coagulation tests; Blood platelets; blood transfusion; Enrollments; Inflammation; Original Research; Patients; Sensors; Trauma; Viscoelasticity; Blood coagulation; blood transfusion; Inflammation; blood coagulation tests

BackgroundViscoelastic assays have widely been used for evaluating coagulopathies but lack the addition of shear stress important to in vivo clot formation. Stasys technology subjects whole blood to shear forces over factor-coated surfaces. Microclot formation is analyzed to determine clot area (CA)...