Exploring matrix factorization techniques for significant genes identification of Alzheimer's disease microarray gene expression data

• Published in: BMC bioinformatics Vol. 12 Suppl 5; no. S5; p. S7
• Main Authors: Kong, Wei, Mou, Xiaoyang, Hu, Xiaohua
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 27.07.2011; BioMed Central; BMC
• Subjects: Algorithms; Alzheimer Disease - genetics; Artificial Intelligence; Cluster Analysis; Databases, Genetic; Gene Expression Profiling - methods; Gene Expression Regulation; Hippocampus - metabolism; Humans; Oligonucleotide Array Sequence Analysis - methods; Proceedings

The wide use of high-throughput DNA microarray technology provide an increasingly detailed view of human transcriptome from hundreds to thousands of genes. Although biomedical researchers typically design microarray experiments to explore specific biological contexts, the relationships between genes...