Exosomal CD73 from serum of patients with melanoma suppresses lymphocyte functions and is associated with therapy resistance to anti-PD-1 agents - Turiello, Roberta; Capone, Mariaelena; Morretta, Elva; Monti, Maria Chiara; Madonna, Gabriele; Azzaro, Rosa; Del Gaudio, Pasquale; Simeone, Ester; Sorrentino, Antonio; Ascierto, Paolo A; Morello, Silvana (Journal for immunotherapy of cancer, 2022)
Keywords: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate - therapeutic use; Antibodies; B7-H1 Antigen - metabolism; Basic Tumor Immunology; Biomarkers; Biotechnology; Blood & organ donations; Cancer; Cancer therapies; Clinical trials; Enzymes; Flow cytometry; GPI-Linked Proteins; Humans; Immunotherapy; Ligands; Lymphocytes - metabolism; Melanoma; Melanoma - drug therapy; Metastasis; Monoclonal antibodies; Nivolumab - pharmacology; Nivolumab - therapeutic use; Phosphatase; Pilot Projects; Proteins; Retrospective Studies; adenosine; melanoma; immunotherapy