Effects of Arctigenin in Proliferation, Migration, and Invasion of Nasopharyngeal Carcinoma 5-8F Cells

• Published in: Anti-cancer agents in medicinal chemistry Vol. 23; no. 10; p. 1211
• Main Authors: Huang, Dongdong, Lu, Rui, Cai, Mingjing, Meng, Jie, He, Shuangba, Zhang, Qingxiang, Meng, Wei
• Format: Journal Article
• Language: English
• Published: Netherlands 01.01.2023
• Subjects: Cell Line, Tumor; Cell Movement; Cell Proliferation - genetics; ErbB Receptors - metabolism; Gene Expression Regulation, Neoplastic; Humans; Nasopharyngeal Carcinoma - genetics; Nasopharyngeal Neoplasms - drug therapy; Nasopharyngeal Neoplasms - genetics; Neoplasm Invasiveness; RNA, Messenger; Arctigenin; migration; nasopharyngeal carcinoma; western blotting; invasion; proliferation

Nasopharyngeal carcinoma (NPC) is a malignant tumor of the nasopharynx. Here, we aimed to understand better the molecular basis for arctigenin (ARG)'s ability to promote NPC 5- 8F cell invasion. We tested the effects of several doses of ARG on 5-8F cells that had been cultured in vitro. We esti...