Detection of BK virus in urine from renal transplant subjects by mass spectrometry

• Published in: Clinical proteomics Vol. 9; no. 1; p. 4
• Main Authors: Konietzny, Rebecca, Fischer, Roman, Ternette, Nicola, Wright, Cynthia A, Turney, Ben W, Chakera, Aron, Hughes, David, Kessler, Benedikt M, Pugh, Chris W
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 26.04.2012; Springer; BMC
• Subjects: BK virus; Care and treatment; Decoy cells; Disease susceptibility; Kidney diseases; Kidneys; Mass spectrometry; Nucleic acids; Organ transplant recipients; Peptides; Renal transplant; Transplantation; Urine proteomics; Viral proteins

The diagnosis and management of BK virus (BKV) reactivation following renal transplantation continues to be a significant clinical problem. Following reactivation of latent virus, impaired cellular immunity enables sustained viral replication to occur in urothelial cells, which potentially leads to...