A pilot open label, single dose trial of fenobam in adults with fragile X syndrome - Berry-Kravis, E; Hessl, D; Coffey, S; Hervey, C; Schneider, A; Yuhas, J; Hutchison, J; Snape, M; Tranfaglia, M; Nguyen, D V; Hagerman, R (Journal of medical genetics, 2009)
Keywords: Administration, Oral; Adolescent; Adult; Biological and medical sciences; Chromatography, Liquid; Chromosome fragility (bloom syndrome, ataxia telangiectasia, fanconi anemia, x-linked mental retardation...); Convulsions & seizures; Female; Fragile X Syndrome - metabolism; Fragile X Syndrome - physiopathology; Fragile X Syndrome - psychology; Fundamental and applied biological sciences. Psychology; General aspects. Genetic counseling; Genetics of eukaryotes. Biological and molecular evolution; Humans; Imidazoles - administration & dosage; Imidazoles - blood; Imidazoles - pharmacokinetics; Inhibition (Psychology); Male; Mass Spectrometry; Medical genetics; Medical sciences; Molecular and cellular biology; Mutation; Neural Inhibition - drug effects; Neuropsychological Tests; Original; Pharmacokinetics; Pilot Projects; Protein synthesis; Proteins; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate - antagonists & inhibitors; Substance abuse treatment; Vertigo; X chromosomes; Young Adult; Human; Chromosome fragility; Fenobam; Tranquillizer; Psychotropic; Adult; Genetics; Fragile X syndrome; Posology