Histological precursors of oesophageal squamous cell carcinoma: results from a 13 year prospective follow up study in a high risk population

• Published in: Gut Vol. 54; no. 2; pp. 187 - 192
• Main Authors: Wang, G-Q, Abnet, C C, Shen, Q, Lewin, K J, Sun, X-D, Roth, M J, Qiao, Y-L, Mark, S D, Dong, Z-W, Taylor, P R, Dawsey, S M
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and British Society of Gastroenterology 01.02.2005; BMJ; BMJ Publishing Group LTD; Copyright 2005 by Gut
• Subjects: Adult; basal cell hyperplasia; BCH; Biological and medical sciences; Biopsy; Cancer; Cancer Institute of the Chinese Academy of Medical Sciences; Carcinoma in Situ - epidemiology; Carcinoma in Situ - pathology; Carcinoma, Squamous Cell - epidemiology; Carcinoma, Squamous Cell - pathology; China; China - epidemiology; CICAMS; CIS; Disease prevention; dysplasia NOS; dysplasia not otherwise specified; Endoscopy; Esophageal Neoplasms - epidemiology; Esophageal Neoplasms - pathology; Esophagitis - epidemiology; Esophagitis - pathology; Esophagoscopy; Esophagus; Female; follow up study; Follow-Up Studies; Gastroenterology. Liver. Pancreas. Abdomen; Hospitals; Humans; IEN; Incidence; Intervention; intraepithelial neoplasia; Iodine; Male; Medical prognosis; Medical sciences; Middle Aged; NCI; Neutrophils; Oesophageal Cancer; oesophageal squamous cell carcinoma; OSCC; Other diseases. Semiology; Precancerous Conditions - epidemiology; Precancerous Conditions - pathology; precursor lesions; Prognosis; Risk Assessment; squamous carcinoma in situ; squamous dysplasia; Tumors; US National Cancer Institute; Asia; China; Human; High risk; Squamous cell carcinoma; Rural environment; Prognosis; Critically ill; Esophageal disease; Esophagus squamous cell carcinoma; Esophagitis; Early stage; Identification; Malignant tumor; Method; Medical screening; Epidemiology; Treatment; Follow up study; Risk factor; Digestive diseases; Diagnosis; Lesion
• ISSN: 0017-5749; 1468-3288; 1458-3288
• DOI: 10.1136/gut.2004.046631

Background: Oesophageal squamous cell carcinoma (OSCC) has a very poor prognosis, which is largely due to late diagnosis. Successful early detection strategies will require identification of clinically relevant precursor lesions that can be targets for screening and treatment. Aims: To identify the...