Functional significance of the sex chromosomes during spermatogenesis

• Published in: Reproduction (Cambridge, England) Vol. 149; no. 6; pp. R265 - R277
• Main Authors: Hu, Yueh-Chiang, Namekawa, Satoshi H
• Format: Journal Article
• Language: English
• Published: England Bioscientifica Ltd 01.06.2015
• Subjects: Animals; Biological Evolution; Male; Meiosis; Mice; Review; Sex Chromosomes; Spermatogenesis - genetics; Testis - physiology

Mammalian sex chromosomes arose from an ordinary pair of autosomes. Over hundreds of millions of years, they have evolved into highly divergent X and Y chromosomes and have become increasingly specialized for male reproduction. Both sex chromosomes have acquired and amplified testis-specific genes,...