Grading systems in head and neck dysplasia: their prognostic value, weaknesses and utility

• Published in: Head & neck oncology Vol. 1; no. 1; p. 11
• Main Authors: Fleskens, Stijn, Slootweg, Piet
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 11.05.2009; BioMed Central
• Subjects: Cancer; Care and treatment; Diagnosis; Dysplasia; Head and neck cancer; Head and Neck Neoplasms - classification; Head and Neck Neoplasms - pathology; Humans; Precancerous Conditions - classification; Precancerous Conditions - pathology; Prognosis; Reproducibility of Results; Review; World Health Organization

Grading of dysplasia, including head and neck lesions, continues to be a hotly debated subject. It is subjective and lacks intra- and inter-observer reproducibility due to the insufficiency of validated morphological criteria and the biological nature of dysplasia. Moreover, due to the absence of a...