Measurement of heritability of myocardial blood flow by positron emission tomography: the Twins Heart Study

• Published in: Heart (British Cardiac Society) Vol. 98; no. 6; pp. 495 - 499
• Main Authors: Su, Shaoyong, Votaw, John, Faber, Tracy, Khan, Durreshahwar, Bremner, J Douglas, Goldberg, Jack, Nichols, Ken, Van Tosh, Andrew, Vaccarino, Viola
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group Ltd and British Cardiovascular Society 01.03.2012; BMJ Publishing Group LTD
• Subjects: Adenosine; Atherosclerosis; Cardiovascular disease; Coronary Circulation - physiology; Coronary flow reserve; Cross-Sectional Studies; cytokines; depression; Diabetes; Family medical history; Flow velocity; genetics; heritability; Humans; Hypertension; Male; Medical imaging; Middle age; Middle Aged; myocardial blood flow; Positron-Emission Tomography; Regional Blood Flow - genetics; Smoking; Studies; twin study; Twins; Twins, Dizygotic; Twins, Monozygotic

ObjectiveTo estimate the heritability of myocardial blood flow (MBF) and coronary flow reserve (CFR) measured with positron emission tomography (PET).DesignCross-sectional twin study.SettingGeneral clinical research centre of a university hospital at Atlanta, USA.PatientsA sample of 180 middle-aged...