Strong association between non alcoholic fatty liver disease (NAFLD) and low 25(OH) vitamin D levels in an adult population with normal serum liver enzymes

• Published in: BMC medicine Vol. 9; no. 1; p. 85
• Main Authors: Barchetta, Ilaria, Angelico, Francesco, Ben, Maria Del, Baroni, Marco Giorgio, Pozzilli, Paolo, Morini, Sergio, Cavallo, Maria Gisella
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 12.07.2011; BioMed Central; BMC
• Subjects: Abdomen - diagnostic imaging; Adult; Fatty Liver - epidemiology; Fatty Liver - etiology; Female; Humans; Liver - enzymology; Male; Metabolic Syndrome - diagnosis; Middle Aged; Non-alcoholic Fatty Liver Disease; Serum - chemistry; Serum - enzymology; Ultrasonography; Vitamin D - blood; Vitamin D Deficiency - complications; Vitamin D Deficiency - epidemiology
• ISSN: 1741-7015; 1741-7015
• DOI: 10.1186/1741-7015-9-85

Hypovitaminosis D has been recently recognized as a worldwide epidemic. Since vitamin D exerts significant metabolic activities, comprising free fatty acids (FFA) flux regulation from the periphery to the liver, its deficiency may promote fat deposition into the hepatocytes. Aim of our study was to...