Actinomyces naeslundii and Eikenella corrodens as rare causes of liver abscesses
A 48-year-old man with an unremarkable medical history was admitted with vague conditions of fever, chills, myalgias and malaise. Physical examination was remarkable for only scleral icterus. Laboratory evaluation revealed elevated aminotransferases, alkaline phosphatase and bilirubin. Imaging demon...
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Published in | BMJ case reports Vol. 2013; p. bcr2013009613 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
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17.07.2013
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Abstract | A 48-year-old man with an unremarkable medical history was admitted with vague conditions of fever, chills, myalgias and malaise. Physical examination was remarkable for only scleral icterus. Laboratory evaluation revealed elevated aminotransferases, alkaline phosphatase and bilirubin. Imaging demonstrated two masses in the right lobe of his liver, which were ultimately drained and cultures demonstrated Actinomyces and Eikenella. He continued to have fever on broad-spectrum antibiotics until catheter drainage of the abscesses was performed. He was eventually discharged in improved condition on amoxicillin-clavulanate. His aminotransferases, alkaline phosphatase and bilirubin continued to improve and he remained afebrile and asymptomatic. A repeat CT 2 months after discharge demonstrated resolution of the abscesses. Actinomyces and Eikenella are rare causes of liver abscesses and treatment requires drainage and an extended course of antibiotics. The polymicrobial character typical of liver abscesses makes antibiotic therapy challenging when cultures reveal rare organisms such as Actinomyces and Eikenella. |
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AbstractList | A 48-year-old man with an unremarkable medical history was admitted with vague conditions of fever, chills, myalgias and malaise. Physical examination was remarkable for only scleral icterus. Laboratory evaluation revealed elevated aminotransferases, alkaline phosphatase and bilirubin. Imaging demonstrated two masses in the right lobe of his liver, which were ultimately drained and cultures demonstrated Actinomyces and Eikenella . He continued to have fever on broad-spectrum antibiotics until catheter drainage of the abscesses was performed. He was eventually discharged in improved condition on amoxicillin-clavulanate. His aminotransferases, alkaline phosphatase and bilirubin continued to improve and he remained afebrile and asymptomatic. A repeat CT 2 months after discharge demonstrated resolution of the abscesses. Actinomyces and Eikenella are rare causes of liver abscesses and treatment requires drainage and an extended course of antibiotics. The polymicrobial character typical of liver abscesses makes antibiotic therapy challenging when cultures reveal rare organisms such as Actinomyces and Eikenella . A 48-year-old man with an unremarkable medical history was admitted with vague conditions of fever, chills, myalgias and malaise. Physical examination was remarkable for only scleral icterus. Laboratory evaluation revealed elevated aminotransferases, alkaline phosphatase and bilirubin. Imaging demonstrated two masses in the right lobe of his liver, which were ultimately drained and cultures demonstrated Actinomyces and Eikenella . He continued to have fever on broad-spectrum antibiotics until catheter drainage of the abscesses was performed. He was eventually discharged in improved condition on amoxicillin-clavulanate. His aminotransferases, alkaline phosphatase and bilirubin continued to improve and he remained afebrile and asymptomatic. A repeat CT 2 months after discharge demonstrated resolution of the abscesses. Actinomyces and Eikenella are rare causes of liver abscesses and treatment requires drainage and an extended course of antibiotics. The polymicrobial character typical of liver abscesses makes antibiotic therapy challenging when cultures reveal rare organisms such as Actinomyces and Eikenella . |
Author | Jahanmir, Jay Smith, Adam J Shin, Terry T Jaqua, Nathan Thomas |
AuthorAffiliation | Department of Internal Medicine , Tripler Army Medical Center , Honolulu, Hawaii , USA |
AuthorAffiliation_xml | – name: Department of Internal Medicine , Tripler Army Medical Center , Honolulu, Hawaii , USA |
Author_xml | – sequence: 1 givenname: Nathan Thomas surname: Jaqua fullname: Jaqua, Nathan Thomas email: nathan.jaqua@gmail.com – sequence: 2 givenname: Adam J surname: Smith fullname: Smith, Adam J email: nathan.jaqua@gmail.com – sequence: 3 givenname: Terry T surname: Shin fullname: Shin, Terry T email: nathan.jaqua@gmail.com – sequence: 4 givenname: Jay surname: Jahanmir fullname: Jahanmir, Jay email: nathan.jaqua@gmail.com |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/23867879$$D View this record in MEDLINE/PubMed |
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SubjectTerms | Abdomen Abscesses Actinomyces Actinomycosis - diagnosis Actinomycosis - drug therapy Anti-Bacterial Agents - therapeutic use Catheters Drainage Drug Therapy, Combination Eikenella corrodens Family medical history Fever Gram-Negative Bacterial Infections - diagnosis Gram-Negative Bacterial Infections - drug therapy Hepatitis Humans Infections Infectious diseases Inflammatory bowel disease Liver Liver Abscess - diagnosis Liver Abscess - drug therapy Male Middle Aged Other Pathogens Rare Disease Tomography, X-Ray Computed USA/Canada Viral infections |
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Title | Actinomyces naeslundii and Eikenella corrodens as rare causes of liver abscesses |
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