Atherosclerosis: From the Disruption of Mitochondrial Membrane Potential to the Potential Interventional Strategies

• Published in: Current medicinal chemistry Vol. 30; no. 38; p. 4355
• Main Authors: Xia, Dexiang, Chen, Yanmei, Luo, Guifang, Wei, Dangheng
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01.01.2023
• Subjects: mitochondrial membrane potential (deltapsi (m)); apoptosis; therapeutics; Atherosclerosis (AS); reactive oxygen species (ROS); NLRP3 inflammasome

Atherosclerosis (AS) is the major factor of cardiovascular disease (CVD) and is characterized by a progressive and chronic inflammatory process in the arterial wall. Recent studies have shown that disruption of the mitochondrial membrane potential (deltapsi (m)) directly affects the electron transpo...