The Fungal Metabolites with Potential Antiplasmodial Activity

• Published in: Current medicinal chemistry Vol. 25; no. 31; p. 3796
• Main Authors: Yang, Bin, Huang, Jingxia, Zhou, Xuefeng, Lin, Xiuping, Liu, Juan, Liao, Shengrong, Wang, Junfeng, Liu, Feng-An, Tao, Huaming, Liu, Yonghong
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01.01.2018
• Subjects: Animals; Antimalarials - chemistry; Antimalarials - isolation & purification; Antimalarials - pharmacology; Biological Products - chemistry; Biological Products - isolation & purification; Biological Products - pharmacology; Cell Line, Tumor; Fungi - chemistry; Fungi - metabolism; Humans; Plasmodium falciparum - drug effects; Structure-Activity Relationship; Antimalarial; natural products; bioactive products; antimicrobial agents; fungus; Plasmodium parasites; marine environments

Malaria caused by Plasmodium parasites is amongst many prevalent public health concerns in several tropical regions of the world. Nowadays, the parasite resistance patterns to most currently used drugs in therapy and insecticides have created an urgent need for new chemical entities exhibiting new m...