Antimicrobial Synthetic Polymers: An Update on Structure-Activity Relationships

• Published in: Current pharmaceutical design Vol. 24; no. 8; p. 855
• Main Authors: Ergene, Cansu, Palermo, Edmund F
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01.01.2018
• Subjects: Antimicrobial; polymer; cationic; peptide; amphiphilic; host defense; hemolytic

The rising incidence of antibiotic-resistant infections, combined with a declining number of new antibiotic drug approvals, has generated an alarming therapeutic gap that critically undermines public health. Host Defense Peptides (HDPs), sometimes referred to as "Nature's Antibiotics"...