Central and peripheral expression and distribution of NUCB2/nesfatin-1

• Published in: Current pharmaceutical design Vol. 19; no. 39; p. 6935
• Main Authors: Goebel-Stengel, Miriam, Wang, Lixin
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01.12.2013
• Subjects: Animals; Brain - metabolism; Calcium-Binding Proteins - metabolism; DNA-Binding Proteins - metabolism; Humans; Nerve Tissue Proteins - metabolism; Neurotransmitter Agents - metabolism

Nesfatin-1 is the N-terminal fragment of nucleobindin-2 (NUCB2). The antibody against nesfatin-1 recognizes both full length of NUCB2 and nesfatin-1, thus the immunolabeling represents NUCB2/nesfatin-1. It has been found that NUCB2/nesfatin-1 is widely distributed in the rodent central nervous syste...