The Therapeutic Potential of Quercetin in Parkinson's Disease: Insights into its Molecular and Cellular Regulation

• Published in: Current drug targets Vol. 21; no. 5; p. 509
• Main Authors: Tamtaji, Omid Reza, Hadinezhad, Tooba, Fallah, Maryam, Shahmirzadi, Arash Rezaei, Taghizadeh, Mohsen, Behnam, Mohammad, Asemi, Zatollah
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01.01.2020
• Subjects: Animals; Antioxidants - metabolism; Antioxidants - pharmacology; Antioxidants - therapeutic use; Dietary Supplements; Dopaminergic Neurons - drug effects; Dopaminergic Neurons - metabolism; Humans; Parkinson Disease - drug therapy; Parkinson Disease - etiology; Quercetin - metabolism; Quercetin - pharmacology; Quercetin - therapeutic use; Synaptic Transmission - drug effects; apoptosis; autophagy; inflammatory cytokines; dopamine; Quercetin; parkinson's disease

Parkinson's disease (PD) is a chronic and progressive neurodegenerative disorder characterized by the progressive death of dopaminergic neurons in the substantia nigra pars compacta (SNc). PD is a multifactorial disorder, with several different factors being suggested to play a synergistic path...