Effect and Mechanism of Curcumin on EZH2 - miR-101 Regulatory Feedback Loop in Multiple Myeloma

• Published in: Current pharmaceutical design Vol. 24; no. 5; p. 564
• Main Authors: Wu, Chuanqing, Ruan, Tuo, Liu, Weizhen, Zhu, Xiaojie, Pan, Juan, Lu, Wen, Yan, Chen, Tao, Kaixiong, Zhang, Weikang, Zhang, Chun
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01.01.2018
• Subjects: SUZ12; multiple myeloma; Curcumin; PRC2; miR-101; EZH2

Multiple myeloma is the second most prevalent hematologic malignancy and thought to be incurable. Therefore, it's urgent to find new drugs for treatment. Some experiments have shown that curcumin might have great potential in treating multiple myeloma, while the mechanism is still unknown. EZH2...