Novel Inhibitors of DNA Repair Enzyme TDP1 Combining Monoterpenoid and Adamantane Fragments - Mozhaitsev, Evgenii S; Zakharenko, Alexandra L; Suslov, Evgeniy V; Korchagina, Dina V; Zakharova, Olga D; Vasil'eva, Inna A; Chepanova, Arina A; Black, Ellena; Patel, Jinal; Chand, Raina; Reynisson, Jóhannes; Leung, Ivanhoe K H; et al. (Anti-cancer agents in medicinal chemistry, 2019)
Keywords: Adamantane - analysis; Catalytic Domain; Cell Line, Tumor; DNA Repair; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Monoterpenes - analysis; Phosphodiesterase Inhibitors - chemistry; Phosphodiesterase Inhibitors - pharmacology; Phosphoric Diester Hydrolases - chemistry; Phosphoric Diester Hydrolases - drug effects; Phosphoric Diester Hydrolases - metabolism; Spectrum Analysis - methods; 3,7-dimethyloctanol; inhibitors; Citronellol; esters; molecular modelling; terpene; chemical space; cytotoxicity