Cardiovascular sequelae of trastuzumab and anthracycline in long-term survivors of breast cancer

• Published in: Heart (British Cardiac Society) Vol. 110; no. 9; pp. 650 - 656
• Main Authors: Glen, Claire, Morrow, Andrew, Roditi, Giles, Hopkins, Tracey, Macpherson, Iain, Stewart, Philip, Petrie, Mark C, Berry, Colin, Epstein, Fred, Lang, Ninian N, Mangion, Kenneth
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group Ltd and British Cardiovascular Society 16.12.2023; BMJ Publishing Group LTD; BMJ Publishing Group
• Series: Original research
• Subjects: Asymptomatic; Biomarkers; Blood pressure; Breast cancer; Cancer therapies; Cardiology; Cardiotoxicity; Cardiovascular disease; Drug dosages; Drug Monitoring; Graft versus host disease; Health services; Heart failure; Hypertension; Magnetic Resonance Imaging; Patients; Radiation therapy; Risk assessment; Risk factors; Software; Special Populations; Surveillance; Toxicity; Womens health; Basel Switzerland; Switzerland; Drug Monitoring; Magnetic Resonance Imaging

ObjectivesLong-term follow-up of patients treated with trastuzumab largely focuses on those with reduced left ventricular ejection fraction (LVEF) on treatment completion. This study sought to evaluate the prevalence of cardiovascular risk factors, overt cardiovascular disease and cardiac imaging ab...