Comparison of the 22nd World Health Organization Model List of Essential Medicines with the explicit criteria for the treatment of chronicity in elderly patients

ObjectivesThis study analysed whether the Model List of Essential Medicines is suitable for elderly patients. Furthermore, it investigated the specific issues that should be considered when prescribing a drug and which drugs should be added to improve the list according to the explicit criteria guid...

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Published inEuropean journal of hospital pharmacy. Science and practice Vol. 30; no. e1; pp. e66 - e69
Main Authors Fernández Fernández, Ramon, Moreno Gil, Queralt, Bessat, Cécile, Roman, Pablo, Sevilla-Sanchez, Daniel
Format Journal Article
LanguageEnglish
Published England British Medical Journal Publishing Group 01.03.2023
BMJ Publishing Group LTD
BMJ Publishing Group
Subjects
Aged
Alzheimer's disease
Constipation
DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS
Drugs
Frailty
GERIATRICS
Health Care Economics and Organizations
Humans
Inappropriate Prescribing - prevention & control
Older people
Original Research
Patients
Polypharmacy
Potentially Inappropriate Medication List
PUBLIC HEALTH
Safety
PUBLIC HEALTH
DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS
Health Care Economics and Organizations
Safety
GERIATRICS
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Abstract ObjectivesThis study analysed whether the Model List of Essential Medicines is suitable for elderly patients. Furthermore, it investigated the specific issues that should be considered when prescribing a drug and which drugs should be added to improve the list according to the explicit criteria guidelines.MethodsA qualitative descriptive review was performed comparing the explicit criteria guidelines of Beers 2019, Laroche, McLeod, NORGEP, PRISCUS, STOPP/START 2014 and Winit-Watjana with the 22nd edition of the Model List of Essential Medicines.ResultsThe Model List of Essential Medicines has 458 drugs. Depending on the explicit criteria considered, there were different numbers of potentially inappropriate medications and potential prescribing omissions. When all explicit criteria were combined, a total of 73 medicines were classified as potentially inappropriate. Using the STOPP/START criteria, 46 potential prescribing omissions were detected. According to these explicit criteria, the Model List of Essential Medicines appeared to lack some medicines.ConclusionsExplicit criteria guidelines have different potential for detecting potentially inappropriate medications. Our findings suggest that some drugs should be added to the next edition of the Model List of Essential Medicines to cover some therapeutic gaps.
AbstractList OBJECTIVESThis study analysed whether the Model List of Essential Medicines is suitable for elderly patients. Furthermore, it investigated the specific issues that should be considered when prescribing a drug and which drugs should be added to improve the list according to the explicit criteria guidelines.METHODSA qualitative descriptive review was performed comparing the explicit criteria guidelines of Beers 2019, Laroche, McLeod, NORGEP, PRISCUS, STOPP/START 2014 and Winit-Watjana with the 22nd edition of the Model List of Essential Medicines.RESULTSThe Model List of Essential Medicines has 458 drugs. Depending on the explicit criteria considered, there were different numbers of potentially inappropriate medications and potential prescribing omissions. When all explicit criteria were combined, a total of 73 medicines were classified as potentially inappropriate. Using the STOPP/START criteria, 46 potential prescribing omissions were detected. According to these explicit criteria, the Model List of Essential Medicines appeared to lack some medicines.CONCLUSIONSExplicit criteria guidelines have different potential for detecting potentially inappropriate medications. Our findings suggest that some drugs should be added to the next edition of the Model List of Essential Medicines to cover some therapeutic gaps.
This study analysed whether the Model List of Essential Medicines is suitable for elderly patients. Furthermore, it investigated the specific issues that should be considered when prescribing a drug and which drugs should be added to improve the list according to the explicit criteria guidelines. A qualitative descriptive review was performed comparing the explicit criteria guidelines of Beers 2019, Laroche, McLeod, NORGEP, PRISCUS, STOPP/START 2014 and Winit-Watjana with the 22nd edition of the Model List of Essential Medicines. The Model List of Essential Medicines has 458 drugs. Depending on the explicit criteria considered, there were different numbers of potentially inappropriate medications and potential prescribing omissions. When all explicit criteria were combined, a total of 73 medicines were classified as potentially inappropriate. Using the STOPP/START criteria, 46 potential prescribing omissions were detected. According to these explicit criteria, the Model List of Essential Medicines appeared to lack some medicines. Explicit criteria guidelines have different potential for detecting potentially inappropriate medications. Our findings suggest that some drugs should be added to the next edition of the Model List of Essential Medicines to cover some therapeutic gaps.
Author Moreno Gil, Queralt
Roman, Pablo
Fernández Fernández, Ramon
Bessat, Cécile
Sevilla-Sanchez, Daniel
AuthorAffiliation 5 Pharmacy Department , Parc Sanitari Pere Virgili , Barcelona , Catalunya , Spain
1 Pharmacy Department , Consorci Sociosanitari de Vilafranca , Vilafranca del Penedes , Barcelona , Spain
3 Department of Internal Medicine , Lausanne University Hospital , Lausanne , Vaud , Switzerland
2 Pharmacy Department , Althaia Foundation of Manresa , Manresa , Catalunya , Spain
4 Primary Health Care Department , Grup Mutua Terrassa , Terrassa , Catalunya , Spain
AuthorAffiliation_xml – name: 3 Department of Internal Medicine , Lausanne University Hospital , Lausanne , Vaud , Switzerland
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Cites_doi 10.1001/archinte.1997.00440390083011
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doi:10.1517/14740338.2013.827660
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Copyright European Association of Hospital Pharmacists 2023. No commercial re-use. See rights and permissions. Published by BMJ.
2022 European Association of Hospital Pharmacists 2022. No commercial re-use. See rights and permissions. Published by BMJ.
2023 European Association of Hospital Pharmacists 2023. No commercial re-use. See rights and permissions. Published by BMJ.
European Association of Hospital Pharmacists 2023. No commercial re-use. See rights and permissions. Published by BMJ. 2023
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DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS
Health Care Economics and Organizations
Safety
GERIATRICS
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Snippet ObjectivesThis study analysed whether the Model List of Essential Medicines is suitable for elderly patients. Furthermore, it investigated the specific issues...
This study analysed whether the Model List of Essential Medicines is suitable for elderly patients. Furthermore, it investigated the specific issues that...
OBJECTIVESThis study analysed whether the Model List of Essential Medicines is suitable for elderly patients. Furthermore, it investigated the specific issues...
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SubjectTerms Aged
Alzheimer's disease
Constipation
DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS
Drugs
Frailty
GERIATRICS
Health Care Economics and Organizations
Humans
Inappropriate Prescribing - prevention & control
Older people
Original Research
Patients
Polypharmacy
Potentially Inappropriate Medication List
PUBLIC HEALTH
Safety
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Title Comparison of the 22nd World Health Organization Model List of Essential Medicines with the explicit criteria for the treatment of chronicity in elderly patients
URI http://dx.doi.org/10.1136/ejhpharm-2022-003237
https://www.ncbi.nlm.nih.gov/pubmed/35523536
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https://www.proquest.com/docview/2788308457
https://search.proquest.com/docview/2661087996
https://pubmed.ncbi.nlm.nih.gov/PMC10086716
Volume 30
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