Opsonic activity in serum from septic infants treated with intravenous immunoglobulin

• Published in: Archives of disease in childhood Vol. 64; no. 4; pp. 530 - 534
• Main Authors: MARODI, L, KALMAR, A, SZABO, I
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health 01.04.1989; BMJ; BMJ Publishing Group LTD
• Subjects: Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Antibiotics; Biological and medical sciences; Complement C3 - analysis; Emergency and intensive care: neonates and children. Prematurity. Sudden death; Female; Humans; Immunization, Passive; Immunoglobulin G - analysis; Infant; Infant, Newborn; Infants; Infusions, Intravenous; Ingestion; Intensive care medicine; Male; Medical sciences; Opsonin Proteins - analysis; Phagocytosis; Sepsis - immunology; Sepsis - therapy; Staphylococcal Infections - immunology; Staphylococcal Infections - therapy; Human; Immunoglobulins; Intravenous administration; Opsonization; Septicemia; Immunotherapy; Infant; Resuscitation

Thirteen infants with staphylococcal sepsis and reduced opsonic activity received infusions of acid treated immunoglobulin together with antibiotics. Opsonic activity (using Staphylococcus aureus (type 42D) as the test organism), haemolytic activity of complement, and concentrations of complement C3...