Point-of-care antibiotic susceptibility testing for gonorrhoea: improving therapeutic options and sparing the use of cephalosporins
Antimicrobial therapy for Neiserria gonorrhoeae is a major public health concern with high rates of resistance to penicillin, tetracycline and fluoroquinolones detected in England and Wales in the Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) (GRASP 2008 Report: Trends in An...
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Published in | Sexually transmitted infections Vol. 86; no. 6; pp. 445 - 446 |
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Main Authors | , , |
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Language | English |
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England
BMJ Publishing Group Ltd
01.11.2010
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Abstract | Antimicrobial therapy for Neiserria gonorrhoeae is a major public health concern with high rates of resistance to penicillin, tetracycline and fluoroquinolones detected in England and Wales in the Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) (GRASP 2008 Report: Trends in Antimicrobial Resistant Gonorrhoea. Known chromosomal mutations associated with penicillin resistance include those altering the structure and function of penicillin-binding proteins (PBPs) and efflux pump activity genes, including penA, ponA, penB, mtrR regulator and possibly penC. 3-5 The other classic resistance mechanism involves TEM-1 type penicillinase production, encoded by the plasmid mediated blaTEM-1 gene. |
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AbstractList | Antimicrobial therapy for Neiserria gonorrhoeae is a major public health concern with high rates of resistance to penicillin, tetracycline and fluoroquinolones detected in England and Wales in the Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) (GRASP 2008 Report: Trends in Antimicrobial Resistant Gonorrhoea. Known chromosomal mutations associated with penicillin resistance include those altering the structure and function of penicillin-binding proteins (PBPs) and efflux pump activity genes, including penA, ponA, penB, mtrR regulator and possibly penC. 3-5 The other classic resistance mechanism involves TEM-1 type penicillinase production, encoded by the plasmid mediated blaTEM-1 gene. No abstract required |
Author | Sadiq, S T Dave, J Butcher, P D |
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Copyright | 2010, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions. Copyright: 2010 (c) 2010, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions. Distributed under a Creative Commons Attribution 4.0 International License |
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References | Trees, Sandul, Whittington 1998; 42 Barry, Klausner 2009; 10 Ito, Yasuda, Yokoi 2004; 48 Liu, Mathies 2009; 27 Siedner, Pandori, Castro 2007; 45 Chisholm, Dave, Ison 2010; 54 Ropp, Hu, Olesky 2002; 46 Morse, Johnson, Biddle 1986; 30 Zhang, Hu 2010; 82 Chisholm, Neal, Alawattegama 2009; 64 Hu, Nandi, Davies 2005; 49 Brannigan, Tirodimos, Zhang 1990; 4 Deguchi, Yasuda, Asano 1995; 39 Ilina, Vereshchagin, Borovskaya 2008; 52 Olesky, Zhao, Rosenberg 2006; 188 |
References_xml | – volume: 10 start-page: 555 year: 2009 article-title: The use of cephalosporins for gonorrhea: the impending problem of resistance publication-title: Expert Opin Pharmacother contributor: fullname: Klausner – volume: 49 start-page: 4327 year: 2005 article-title: High-level chromosomally mediated tetracycline resistance in Neisseria gonorrhoeae results from a point mutation in the rpsJ gene encoding ribosomal protein S10 in combination with the mtrR and penB resistance determinants publication-title: Antimicrob Agents Chemother contributor: fullname: Davies – volume: 82 start-page: 1921 year: 2010 article-title: Single quantum dot-based nanosensor for multiple DNA detection publication-title: Anal Chem contributor: fullname: Hu – volume: 4 start-page: 913 year: 1990 article-title: Insertion of an extra amino acid is the main cause of the low affinity of penicillin-binding protein 2 in penicillin-resistant strains of Neisseria gonorrhoeae publication-title: Mol Microbiol contributor: fullname: Zhang – volume: 27 start-page: 572 year: 2009 article-title: Integrated microfluidic systems for high-performance genetic analysis publication-title: Trends Biotechnol contributor: fullname: Mathies – volume: 188 start-page: 2300 year: 2006 article-title: Porin-mediated antibiotic resistance in Neisseria gonorrhoeae: ion, solute, and antibiotic permeation through PIB proteins with penB mutations publication-title: J Bacteriol contributor: fullname: Rosenberg – volume: 52 start-page: 2175 year: 2008 article-title: Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains publication-title: Antimicrob Agents Chemother contributor: fullname: Borovskaya – volume: 39 start-page: 561 year: 1995 article-title: DNA gyrase mutations in quinolone-resistant clinical isolates of Neisseria gonorrhoeae publication-title: Antimicrob Agents Chemother contributor: fullname: Asano – volume: 46 start-page: 769 year: 2002 article-title: Mutations in ponA, the gene encoding penicillin-binding protein 1, and a novel locus, penC, are required for high-level chromosomally mediated penicillin resistance in Neisseria gonorrhoeae publication-title: Antimicrob Agents Chemother contributor: fullname: Olesky – volume: 64 start-page: 353 year: 2009 article-title: Emergence of high-level azithromycin resistance in Neisseria gonorrhoeae in England and Wales publication-title: J Antimicrob Chemother contributor: fullname: Alawattegama – volume: 45 start-page: 1250 year: 2007 article-title: Real-time PCR assay for detection of quinolone-resistant Neisseria gonorrhoeae in urine samples publication-title: J Clin Microbiol contributor: fullname: Castro – volume: 30 start-page: 664 year: 1986 article-title: High-level tetracycline resistance in Neisseria gonorrhoeae is result of acquisition of streptococcal tetM determinant publication-title: Antimicrob Agents Chemother contributor: fullname: Biddle – volume: 48 start-page: 3185 year: 2004 article-title: Remarkable increase in central Japan in 2001–2002 of Neisseria gonorrhoeae isolates with decreased susceptibility to penicillin, tetracycline, oral cephalosporins, and fluoroquinolones publication-title: Antimicrob Agents Chemother contributor: fullname: Yokoi – volume: 42 start-page: 2103 year: 1998 article-title: Identification of novel mutation patterns in the parC gene of ciprofloxacin-resistant isolates of Neisseria gonorrhoeae publication-title: Antimicrob Agents Chemother contributor: fullname: Whittington – volume: 54 start-page: 3812 year: 2010 article-title: High-level Azithromycin resistance occurs in Neisseria gonorrhoeae as a result of a single point mutation in the 23S rRNA genes publication-title: Antimicrob Agents Chemother contributor: fullname: Ison |
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SubjectTerms | Anti-Bacterial Agents - therapeutic use antibiotic resistance antibiotic sensitivy Antibiotics Antimicrobial agents Cephalosporins - therapeutic use Collaboration diagnosis Drug Resistance, Multiple, Bacterial - genetics fluoroquinolone Genes Gonorrhea Gonorrhea - drug therapy gonorrhoea Humans Microbial Sensitivity Tests - methods Mutation Mutation - genetics Neisseria gonorrhoeae Penicillin Point-of-Care Systems point-of-care technology Surveillance |
Title | Point-of-care antibiotic susceptibility testing for gonorrhoea: improving therapeutic options and sparing the use of cephalosporins |
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