Serum amyloid A (SAA) variations in patients with cancer: correlation with disease activity, stage, primary site, and prognosis

• Published in: Journal of clinical pathology Vol. 39; no. 7; pp. 794 - 797
• Main Authors: Biran, H, Friedman, N, Neumann, L, Pras, M, Shainkin-Kestenbaum, R
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and Association of Clinical Pathologists 01.07.1986; BMJ; BMJ Publishing Group LTD
• Subjects: Amyloid - metabolism; Biological and medical sciences; Breast Neoplasms - blood; Colonic Neoplasms - blood; Female; Host-tumor relations. Immunology. Biological markers; Humans; Lung Neoplasms - blood; Male; Medical sciences; Neoplasm Staging; Neoplasms - blood; Prognosis; Rectal Neoplasms - blood; Serum Amyloid A Protein - metabolism; Time Factors; Tumors; Human; Clinical stage; Prognosis; Biological marker; Serum; Tumor; Amyloid; Apolipoproteins

Serum amyloid A (SAA) was determined in 160 patients with cancer. Active disease was associated with high titre compared with the titre in non-active condition (31.8 v 5.8 micrograms/ml, respectively; p = 0.0002). SAA value showed a direct correlation with the stage of the disease: it was lowest at...