Statics and dynamics of malaria infection in Anopheles mosquitoes

The classic formulae in malaria epidemiology are reviewed that relate entomological parameters to malaria transmission, including mosquito survivorship and age-at-infection, the stability index (S), the human blood index (HBI), proportion of infected mosquitoes, the sporozoite rate, the entomologica...

Full description

Saved in:
Bibliographic Details
Published inMalaria journal Vol. 3; no. 1; p. 13
Main Authors Smith, David L, McKenzie, F Ellis
Format Journal Article
LanguageEnglish
Published England BioMed Central Ltd 04.06.2004
BioMed Central
BMC
Subjects
Animals
Anopheles
Anopheles - parasitology
Anopheles - physiology
Humans
Insect Vectors - parasitology
Insect Vectors - physiology
Malaria - epidemiology
Malaria - prevention & control
Malaria - transmission
Models, Biological
Review
Online AccessGet full text

Cover

More Information
Summary:The classic formulae in malaria epidemiology are reviewed that relate entomological parameters to malaria transmission, including mosquito survivorship and age-at-infection, the stability index (S), the human blood index (HBI), proportion of infected mosquitoes, the sporozoite rate, the entomological inoculation rate (EIR), vectorial capacity (C) and the basic reproductive number (R0). The synthesis emphasizes the relationships among classic formulae and reformulates a simple dynamic model for the proportion of infected humans. The classic formulae are related to formulae from cyclical feeding models, and some inconsistencies are noted. The classic formulae are used to to illustrate how malaria control reduces malaria transmission and show that increased mosquito mortality has an effect even larger than was proposed by Macdonald in the 1950's.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ObjectType-Article-2
ObjectType-Feature-3
ObjectType-Review-1
ISSN:1475-2875
1475-2875
DOI:10.1186/1475-2875-3-13