Impact of age on excess risk of coronary heart disease in patients with familial hypercholesterolaemia

• Published in: Heart (British Cardiac Society) Vol. 104; no. 19; pp. 1600 - 1607
• Main Authors: Mundal, Liv J, Igland, Jannicke, Veierød, Marit B, Holven, Kirsten Bjørklund, Ose, Leiv, Selmer, Randi Marie, Wisloff, Torbjorn, Kristiansen, Ivar S, Tell, Grethe S, Leren, Trond P, Retterstøl, Kjetil
• Format: Journal Article
• Language: English; Norwegian
• Published: England BMJ Publishing Group LTD 01.10.2018; BMJ Publishing Group
• Series: Original research article
• Subjects: Adult; Age Factors; Aged; Cardiovascular disease; Coronary Artery Disease; Coronary Disease - epidemiology; Female; Health risk assessment; Hospitalization - statistics & numerical data; Humans; Hyperlipoproteinemia Type II - diagnosis; Hyperlipoproteinemia Type II - epidemiology; Incidence; Low density lipoprotein; Male; Middle Aged; Mortality; Norway - epidemiology; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Sex Factors; Norway; coronary artery disease; genetics; cardiac risk factors and prevention; lipoproteins and hyperlipidemia; acute myocardial infarction

ObjectiveThe primary objective was to study the risk of acute myocardial infarction (AMI) and coronary heart disease (CHD) in patients with familial hypercholesterolaemia (FH) and compare with the risk in the general population.MethodsPatients with an FH mutation but without prior AMI (n=3071) and w...