Systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a multisystem relapsing and remitting autoimmune disease. The management of this condition in pregnancy provides the obstetrician, physician, and general practitioner with particular challenges and concerns related to the mother and her baby. Here, Mackillop et...
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Published in | BMJ Vol. 335; no. 7626; pp. 933 - 936 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
London
British Medical Journal Publishing Group
03.11.2007
British Medical Association BMJ Publishing Group LTD BMJ Publishing Group BMJ Publishing Group Ltd |
Edition | International edition |
Series | Pregnancy Plus |
Subjects | |
Online Access | Get full text |
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Abstract | Systemic lupus erythematosus (SLE) is a multisystem relapsing and remitting autoimmune disease. The management of this condition in pregnancy provides the obstetrician, physician, and general practitioner with particular challenges and concerns related to the mother and her baby. Here, Mackillop et al discuss these challenges and talks about how pregnancy affect SLE and vice versa. Moreover, they conclude that SLE and the overlap condition of the antiphospholipid syndrome present several challenges in managing a pregnant woman and her fetus. A successful pregnancy outcome depends on stratification of risk at the outset (ideally before pregnancy) and careful and appropriate monitoring during the pregnancy. Should the disease flare up, aggressive but considered management is advocated to reduce maternal and fetal morbidity. |
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AbstractList | Systemic lupus erythematosus in pregnancy brings risks for the mother, and possible harm to the fetus if the disease is treated. This article discusses the challenges of management Pregnancy Plus series. Scenario-based account of the problems for mother and baby in the management of systemic lupus erythematosus (SLE) in pregnancy. [(BNI unique abstract)] 11 references Systemic lupus erythematosus (SLE) is a multisystem relapsing and remitting autoimmune disease. The management of this condition in pregnancy provides the obstetrician, physician, and general practitioner with particular challenges and concerns related to the mother and her baby. Here, Mackillop et al discuss these challenges and talks about how pregnancy affect SLE and vice versa. Moreover, they conclude that SLE and the overlap condition of the antiphospholipid syndrome present several challenges in managing a pregnant woman and her fetus. A successful pregnancy outcome depends on stratification of risk at the outset (ideally before pregnancy) and careful and appropriate monitoring during the pregnancy. Should the disease flare up, aggressive but considered management is advocated to reduce maternal and fetal morbidity. |
Author | Mackillop, Lucy H Germain, Sarah J Nelson-Piercy, Catherine |
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Keywords | Medicine Immunopathology Connective tissue disease Skin disease Systemic lupus erythematosus Systemic disease Autoimmune disease |
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References | 2007; 334 2005; 52 2006; 8 2003; 16 2006; 19 2004; 50 2006; 20 2007; 369 1996; 35 2006; 332 2003; 10 17307106 - Lancet. 2007 Feb 17;369(9561):587-96 15077285 - Arthritis Rheum. 2004 Apr;50(4):1028-39 16736410 - J Nephrol. 2006 Mar-Apr;19(2):135-43 16979532 - Best Pract Res Clin Rheumatol. 2006 Aug;20(4):685-94 16613963 - BMJ. 2006 Apr 15;332(7546):890-4 12768062 - J Nephrol. 2003 Mar-Apr;16(2):161-7 12798544 - Obstet Gynecol. 2003 Jun;101(6):1333-44 15692988 - Arthritis Rheum. 2005 Feb;52(2):514-21 8612024 - Br J Rheumatol. 1996 Feb;35(2):133-8 17585161 - BMJ. 2007 Jun 23;334(7607):1318-21 16712713 - Arthritis Res Ther. 2006;8(3):209 |
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Snippet | Systemic lupus erythematosus in pregnancy brings risks for the mother, and possible harm to the fetus if the disease is treated. This article discusses the... Systemic lupus erythematosus (SLE) is a multisystem relapsing and remitting autoimmune disease. The management of this condition in pregnancy provides the... Pregnancy Plus series. Scenario-based account of the problems for mother and baby in the management of systemic lupus erythematosus (SLE) in pregnancy. [(BNI... |
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SubjectTerms | Adult Analgesics - therapeutic use Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Biological and medical sciences Counseling Disease management Female Fetal Diseases - diagnosis General aspects Humans Immune system Immunosuppressive Agents - therapeutic use Infant mortality Lupus Lupus Erythematosus, Systemic - therapy Medical sciences Medical treatment Practice Preconception Care - methods Pregnancy Pregnancy Complications - therapy Prenatal Care - methods Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis |
Title | Systemic lupus erythematosus |
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