Systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a multisystem relapsing and remitting autoimmune disease. The management of this condition in pregnancy provides the obstetrician, physician, and general practitioner with particular challenges and concerns related to the mother and her baby. Here, Mackillop et...

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Published inBMJ Vol. 335; no. 7626; pp. 933 - 936
Main Authors Mackillop, Lucy H, Germain, Sarah J, Nelson-Piercy, Catherine
Format Journal Article
LanguageEnglish
Published London British Medical Journal Publishing Group 03.11.2007
British Medical Association
BMJ Publishing Group LTD
BMJ Publishing Group
BMJ Publishing Group Ltd
EditionInternational edition
SeriesPregnancy Plus
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Abstract Systemic lupus erythematosus (SLE) is a multisystem relapsing and remitting autoimmune disease. The management of this condition in pregnancy provides the obstetrician, physician, and general practitioner with particular challenges and concerns related to the mother and her baby. Here, Mackillop et al discuss these challenges and talks about how pregnancy affect SLE and vice versa. Moreover, they conclude that SLE and the overlap condition of the antiphospholipid syndrome present several challenges in managing a pregnant woman and her fetus. A successful pregnancy outcome depends on stratification of risk at the outset (ideally before pregnancy) and careful and appropriate monitoring during the pregnancy. Should the disease flare up, aggressive but considered management is advocated to reduce maternal and fetal morbidity.
AbstractList Systemic lupus erythematosus in pregnancy brings risks for the mother, and possible harm to the fetus if the disease is treated. This article discusses the challenges of management
Pregnancy Plus series. Scenario-based account of the problems for mother and baby in the management of systemic lupus erythematosus (SLE) in pregnancy. [(BNI unique abstract)] 11 references
Systemic lupus erythematosus (SLE) is a multisystem relapsing and remitting autoimmune disease. The management of this condition in pregnancy provides the obstetrician, physician, and general practitioner with particular challenges and concerns related to the mother and her baby. Here, Mackillop et al discuss these challenges and talks about how pregnancy affect SLE and vice versa. Moreover, they conclude that SLE and the overlap condition of the antiphospholipid syndrome present several challenges in managing a pregnant woman and her fetus. A successful pregnancy outcome depends on stratification of risk at the outset (ideally before pregnancy) and careful and appropriate monitoring during the pregnancy. Should the disease flare up, aggressive but considered management is advocated to reduce maternal and fetal morbidity.
Author Mackillop, Lucy H
Germain, Sarah J
Nelson-Piercy, Catherine
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  givenname: Catherine
  surname: Nelson-Piercy
  fullname: Nelson-Piercy, Catherine
  email: lucymackillop@hotmail.com
  organization: Queen Charlotte's and Chelsea Hospital and St Thomas' Hospital, London
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Issue 7626
Keywords Medicine
Immunopathology
Connective tissue disease
Skin disease
Systemic lupus erythematosus
Systemic disease
Autoimmune disease
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This is one of a series of occasional articles about how to manage a pre-existing medical condition during pregnancy. If you would like to suggest a topic for this series please email Amy Davis (adavis@bmj.com)
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Snippet Systemic lupus erythematosus in pregnancy brings risks for the mother, and possible harm to the fetus if the disease is treated. This article discusses the...
Systemic lupus erythematosus (SLE) is a multisystem relapsing and remitting autoimmune disease. The management of this condition in pregnancy provides the...
Pregnancy Plus series. Scenario-based account of the problems for mother and baby in the management of systemic lupus erythematosus (SLE) in pregnancy. [(BNI...
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StartPage 933
SubjectTerms Adult
Analgesics - therapeutic use
Anti-Inflammatory Agents, Non-Steroidal - therapeutic use
Biological and medical sciences
Counseling
Disease management
Female
Fetal Diseases - diagnosis
General aspects
Humans
Immune system
Immunosuppressive Agents - therapeutic use
Infant mortality
Lupus
Lupus Erythematosus, Systemic - therapy
Medical sciences
Medical treatment
Practice
Preconception Care - methods
Pregnancy
Pregnancy Complications - therapy
Prenatal Care - methods
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Title Systemic lupus erythematosus
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