Size-regulated group separation of CoFe2O4 nanoparticles using centrifuge and their magnetic resonance contrast properties
Magnetic nanoparticle (MNP)-based magnetic resonance imaging (MRI) contrast agents (CAs) have been the subject of extensive research over recent decades. The particle size of MNPs varies widely and is known to influence their physicochemical and pharmacokinetic properties. There are two commonly use...
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| Published in | Nanoscale research letters Vol. 8; no. 1; p. 376 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
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New York
Springer New York
03.09.2013
BioMed Central Ltd Springer |
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| Abstract | Magnetic nanoparticle (MNP)-based magnetic resonance imaging (MRI) contrast agents (CAs) have been the subject of extensive research over recent decades. The particle size of MNPs varies widely and is known to influence their physicochemical and pharmacokinetic properties. There are two commonly used methods for synthesizing MNPs, organometallic and aqueous solution coprecipitation. The former has the advantage of being able to control the particle size more effectively; however, the resulting particles require a hydrophilic coating in order to be rendered water soluble. The MNPs produced using the latter method are intrinsically water soluble, but they have a relatively wide particle size distribution. Size-controlled water-soluble MNPs have great potential as MRI CAs and in cell sorting and labeling applications. In the present study, we synthesized CoFe
2
O
4
MNPs using an aqueous solution coprecipitation method. The MNPs were subsequently separated into four groups depending on size, by the use of centrifugation at different speeds. The crystal shapes and size distributions of the particles in the four groups were measured and confirmed by transmission electron microscopy and dynamic light scattering. Using X-ray diffraction analysis, the MNPs were found to have an inverse spinel structure. Four MNP groups with well-selected semi-Gaussian-like diameter distributions were obtained, with measured T
2
relaxivities (
r
2
) at 4.7 T and room temperature in the range of 60 to 300 mM
−1
s
−1
, depending on the particle size. This size regulation method has great promise for applications that require homogeneous-sized MNPs made by an aqueous solution coprecipitation method. Any group of the CoFe
2
O
4
MNPs could be used as initial base cores of MRI T
2
CAs, with almost unique T
2
relaxivity owing to size regulation. The methodology reported here opens up many possibilities for biosensing applications and disease diagnosis.
PACS
75.75.Fk, 78.67.Bf, 61.46.Df |
|---|---|
| AbstractList | Magnetic nanoparticle (MNP)-based magnetic resonance imaging (MRI) contrast agents (CAs) have been the subject of extensive research over recent decades. The particle size of MNPs varies widely and is known to influence their physicochemical and pharmacokinetic properties. There are two commonly used methods for synthesizing MNPs, organometallic and aqueous solution coprecipitation. The former has the advantage of being able to control the particle size more effectively; however, the resulting particles require a hydrophilic coating in order to be rendered water soluble. The MNPs produced using the latter method are intrinsically water soluble, but they have a relatively wide particle size distribution. Size-controlled water-soluble MNPs have great potential as MRI CAs and in cell sorting and labeling applications. In the present study, we synthesized CoFe
2
O
4
MNPs using an aqueous solution coprecipitation method. The MNPs were subsequently separated into four groups depending on size, by the use of centrifugation at different speeds. The crystal shapes and size distributions of the particles in the four groups were measured and confirmed by transmission electron microscopy and dynamic light scattering. Using X-ray diffraction analysis, the MNPs were found to have an inverse spinel structure. Four MNP groups with well-selected semi-Gaussian-like diameter distributions were obtained, with measured T
2
relaxivities (
r
2
) at 4.7 T and room temperature in the range of 60 to 300 mM
−1
s
−1
, depending on the particle size. This size regulation method has great promise for applications that require homogeneous-sized MNPs made by an aqueous solution coprecipitation method. Any group of the CoFe
2
O
4
MNPs could be used as initial base cores of MRI T
2
CAs, with almost unique T
2
relaxivity owing to size regulation. The methodology reported here opens up many possibilities for biosensing applications and disease diagnosis.
PACS
75.75.Fk, 78.67.Bf, 61.46.Df Magnetic nanoparticle (MNP)-based magnetic resonance imaging (MRI) contrast agents (CAs) have been the subject of extensive research over recent decades. The particle size of MNPs varies widely and is known to influence their physicochemical and pharmacokinetic properties. There are two commonly used methods for synthesizing MNPs, organometallic and aqueous solution coprecipitation. The former has the advantage of being able to control the particle size more effectively; however, the resulting particles require a hydrophilic coating in order to be rendered water soluble. The MNPs produced using the latter method are intrinsically water soluble, but they have a relatively wide particle size distribution. Size-controlled water-soluble MNPs have great potential as MRI CAs and in cell sorting and labeling applications. In the present study, we synthesized CoFe2O4 MNPs using an aqueous solution coprecipitation method. The MNPs were subsequently separated into four groups depending on size, by the use of centrifugation at different speeds. The crystal shapes and size distributions of the particles in the four groups were measured and confirmed by transmission electron microscopy and dynamic light scattering. Using X-ray diffraction analysis, the MNPs were found to have an inverse spinel structure. Four MNP groups with well-selected semi-Gaussian-like diameter distributions were obtained, with measured T2 relaxivities (r2) at 4.7 T and room temperature in the range of 60 to 300 mM−1s−1, depending on the particle size. This size regulation method has great promise for applications that require homogeneous-sized MNPs made by an aqueous solution coprecipitation method. Any group of the CoFe2O4 MNPs could be used as initial base cores of MRI T2 CAs, with almost unique T2 relaxivity owing to size regulation. The methodology reported here opens up many possibilities for biosensing applications and disease diagnosis. PACS: 75.75.Fk, 78.67.Bf, 61.46.Df Magnetic nanoparticle (MNP)-based magnetic resonance imaging (MRI) contrast agents (CAs) have been the subject of extensive research over recent decades. The particle size of MNPs varies widely and is known to influence their physicochemical and pharmacokinetic properties. There are two commonly used methods for synthesizing MNPs, organometallic and aqueous solution coprecipitation. The former has the advantage of being able to control the particle size more effectively; however, the resulting particles require a hydrophilic coating in order to be rendered water soluble. The MNPs produced using the latter method are intrinsically water soluble, but they have a relatively wide particle size distribution. Size-controlled water-soluble MNPs have great potential as MRI CAs and in cell sorting and labeling applications. In the present study, we synthesized CoFe2O4 MNPs using an aqueous solution coprecipitation method. The MNPs were subsequently separated into four groups depending on size, by the use of centrifugation at different speeds. The crystal shapes and size distributions of the particles in the four groups were measured and confirmed by transmission electron microscopy and dynamic light scattering. Using X-ray diffraction analysis, the MNPs were found to have an inverse spinel structure. Four MNP groups with well-selected semi-Gaussian-like diameter distributions were obtained, with measured T2 relaxivities (r2) at 4.7 T and room temperature in the range of 60 to 300 mM-1s-1, depending on the particle size. This size regulation method has great promise for applications that require homogeneous-sized MNPs made by an aqueous solution coprecipitation method. Any group of the CoFe2O4 MNPs could be used as initial base cores of MRI T2 CAs, with almost unique T2 relaxivity owing to size regulation. The methodology reported here opens up many possibilities for biosensing applications and disease diagnosis. PACS: 75.75.Fk, 78.67.Bf, 61.46.Df. Magnetic nanoparticle (MNP)-based magnetic resonance imaging (MRI) contrast agents (CAs) have been the subject of extensive research over recent decades. The particle size of MNPs varies widely and is known to influence their physicochemical and pharmacokinetic properties. There are two commonly used methods for synthesizing MNPs, organometallic and aqueous solution coprecipitation. The former has the advantage of being able to control the particle size more effectively; however, the resulting particles require a hydrophilic coating in order to be rendered water soluble. The MNPs produced using the latter method are intrinsically water soluble, but they have a relatively wide particle size distribution. Size-controlled water-soluble MNPs have great potential as MRI CAs and in cell sorting and labeling applications. In the present study, we synthesized CoFe2O4 MNPs using an aqueous solution coprecipitation method. The MNPs were subsequently separated into four groups depending on size, by the use of centrifugation at different speeds. The crystal shapes and size distributions of the particles in the four groups were measured and confirmed by transmission electron microscopy and dynamic light scattering. Using X-ray diffraction analysis, the MNPs were found to have an inverse spinel structure. Four MNP groups with well-selected semi-Gaussian-like diameter distributions were obtained, with measured T2 relaxivities (r2) at 4.7 T and room temperature in the range of 60 to 300 mM-1s-1, depending on the particle size. This size regulation method has great promise for applications that require homogeneous-sized MNPs made by an aqueous solution coprecipitation method. Any group of the CoFe2O4 MNPs could be used as initial base cores of MRI T2 CAs, with almost unique T2 relaxivity owing to size regulation. The methodology reported here opens up many possibilities for biosensing applications and disease diagnosis. PACS: 75.75.Fk, 78.67.Bf, 61.46.Df.Magnetic nanoparticle (MNP)-based magnetic resonance imaging (MRI) contrast agents (CAs) have been the subject of extensive research over recent decades. The particle size of MNPs varies widely and is known to influence their physicochemical and pharmacokinetic properties. There are two commonly used methods for synthesizing MNPs, organometallic and aqueous solution coprecipitation. The former has the advantage of being able to control the particle size more effectively; however, the resulting particles require a hydrophilic coating in order to be rendered water soluble. The MNPs produced using the latter method are intrinsically water soluble, but they have a relatively wide particle size distribution. Size-controlled water-soluble MNPs have great potential as MRI CAs and in cell sorting and labeling applications. In the present study, we synthesized CoFe2O4 MNPs using an aqueous solution coprecipitation method. The MNPs were subsequently separated into four groups depending on size, by the use of centrifugation at different speeds. The crystal shapes and size distributions of the particles in the four groups were measured and confirmed by transmission electron microscopy and dynamic light scattering. Using X-ray diffraction analysis, the MNPs were found to have an inverse spinel structure. Four MNP groups with well-selected semi-Gaussian-like diameter distributions were obtained, with measured T2 relaxivities (r2) at 4.7 T and room temperature in the range of 60 to 300 mM-1s-1, depending on the particle size. This size regulation method has great promise for applications that require homogeneous-sized MNPs made by an aqueous solution coprecipitation method. Any group of the CoFe2O4 MNPs could be used as initial base cores of MRI T2 CAs, with almost unique T2 relaxivity owing to size regulation. The methodology reported here opens up many possibilities for biosensing applications and disease diagnosis. PACS: 75.75.Fk, 78.67.Bf, 61.46.Df. Magnetic nanoparticle (MNP)-based magnetic resonance imaging (MRI) contrast agents (CAs) have been the subject of extensive research over recent decades. The particle size of MNPs varies widely and is known to influence their physicochemical and pharmacokinetic properties. There are two commonly used methods for synthesizing MNPs, organometallic and aqueous solution coprecipitation. The former has the advantage of being able to control the particle size more effectively; however, the resulting particles require a hydrophilic coating in order to be rendered water soluble. The MNPs produced using the latter method are intrinsically water soluble, but they have a relatively wide particle size distribution. Size-controlled water-soluble MNPs have great potential as MRI CAs and in cell sorting and labeling applications. In the present study, we synthesized CoFe 2 O 4 MNPs using an aqueous solution coprecipitation method. The MNPs were subsequently separated into four groups depending on size, by the use of centrifugation at different speeds. The crystal shapes and size distributions of the particles in the four groups were measured and confirmed by transmission electron microscopy and dynamic light scattering. Using X-ray diffraction analysis, the MNPs were found to have an inverse spinel structure. Four MNP groups with well-selected semi-Gaussian-like diameter distributions were obtained, with measured T 2 relaxivities ( r 2 ) at 4.7 T and room temperature in the range of 60 to 300 mM −1 s −1 , depending on the particle size. This size regulation method has great promise for applications that require homogeneous-sized MNPs made by an aqueous solution coprecipitation method. Any group of the CoFe 2 O 4 MNPs could be used as initial base cores of MRI T 2 CAs, with almost unique T 2 relaxivity owing to size regulation. The methodology reported here opens up many possibilities for biosensing applications and disease diagnosis. |
| ArticleNumber | 376 |
| Author | Yeom, Areum Lim, Yong Taik Kim, Young-Nam Hong, Kwan Soo Jeong, Heejeong Lee, Hyunseung Kang, Jongeun |
| AuthorAffiliation | 2 Graduate School of Analytical Science and Technology, Chungnam National University, Daejeon 305-764, South Korea 1 Center for MR Research, Korea Basic Science Institute, Cheongwon 363-883, South Korea |
| AuthorAffiliation_xml | – name: 1 Center for MR Research, Korea Basic Science Institute, Cheongwon 363-883, South Korea – name: 2 Graduate School of Analytical Science and Technology, Chungnam National University, Daejeon 305-764, South Korea |
| Author_xml | – sequence: 1 givenname: Jongeun surname: Kang fullname: Kang, Jongeun organization: Center for MR Research, Korea Basic Science Institute, Graduate School of Analytical Science and Technology, Chungnam National University – sequence: 2 givenname: Hyunseung surname: Lee fullname: Lee, Hyunseung organization: Center for MR Research, Korea Basic Science Institute – sequence: 3 givenname: Young-Nam surname: Kim fullname: Kim, Young-Nam organization: Center for MR Research, Korea Basic Science Institute – sequence: 4 givenname: Areum surname: Yeom fullname: Yeom, Areum organization: Center for MR Research, Korea Basic Science Institute – sequence: 5 givenname: Heejeong surname: Jeong fullname: Jeong, Heejeong organization: Center for MR Research, Korea Basic Science Institute – sequence: 6 givenname: Yong Taik surname: Lim fullname: Lim, Yong Taik organization: Graduate School of Analytical Science and Technology, Chungnam National University – sequence: 7 givenname: Kwan Soo surname: Hong fullname: Hong, Kwan Soo email: kshong@kbsi.re.kr organization: Center for MR Research, Korea Basic Science Institute, Graduate School of Analytical Science and Technology, Chungnam National University |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/24004536$$D View this record in MEDLINE/PubMed |
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| CitedBy_id | crossref_primary_10_1007_s10334_023_01072_4 crossref_primary_10_1134_S0036023620080173 crossref_primary_10_1007_s10948_019_5051_2 crossref_primary_10_1016_j_ceramint_2020_12_042 crossref_primary_10_1134_S0036023620100186 crossref_primary_10_1039_C5NJ00009B crossref_primary_10_1080_15421406_2019_1578500 crossref_primary_10_1016_j_jpcs_2017_12_056 crossref_primary_10_6023_A23040189 crossref_primary_10_3390_ijms21103476 crossref_primary_10_1039_C4DT02144D crossref_primary_10_1049_iet_nbt_2019_0210 crossref_primary_10_1088_1361_6528_ab3f17 crossref_primary_10_1016_j_ceramint_2020_07_298 crossref_primary_10_1039_C6CP06012A |
| Cites_doi | 10.1002/anie.200602866 10.1557/JMR.1992.1856 10.1038/nm1700 10.1021/ja0422155 10.1346/CCMN.1999.0470608 10.1073/pnas.0403918101 10.1021/cm049221k 10.1016/j.jmmm.2004.04.035 10.1039/b409601k 10.1016/j.jmmm.2004.05.022 10.1021/cr068445e 10.1109/TIP.2010.2048612 10.1021/la1015077 10.1016/j.biomaterials.2007.08.050 10.1021/nn1019779 10.1016/S0921-4526(03)00322-3 10.1021/jp905776g 10.1002/smll.200500360 10.1021/nl071099b 10.1016/j.biomaterials.2008.05.015 10.1148/radiol.2351040094 10.3109/02652049609026013 10.1021/bc050050z 10.1063/1.1709207 10.1002/nbm.1011 10.1088/0957-4484/19/16/165101 10.1073/pnas.1000386107 |
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| Keywords | Magnetic resonance imaging Relaxivity Particle size regulation Magnetic nanoparticles |
| Language | English |
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| References | Sonvico, Mornet, Vasseur, Dubernet, Jaillard, Degrouard, Hoebeke, Duguet, Colombo, Couvreur (CR8) 2005; 16 Mulder, Strijkers, van Tilborg, Griffioen, Nicolay (CR17) 2006; 19 Matuszewski, Persigehl, Wall, Schwindt, Tombach, Fobker, Poremba, Ebert, Heindel, Bremer (CR11) 2005; 235 Jana, Chen, Peng (CR15) 2004; 16 Judenhofer, Wehrl, Newport, Catana, Siegel, Becker, Thielscher, Kneilling, Lichy, Eichner, Klingel, Reischl, Widmaier, Rocken, Nutt, Machulla, Uludag, Cherry, Claussen, Pichler (CR1) 2008; 14 Lee, Jeong, Shin, Kim, Kim (CR20) 2004; 282 Branca, Cleveland, Fubara, Kumar, Maronpot, Leuschner, Warren, Driehuys (CR7) 2010; 107 Bennewitz, Lobo, Nkansah, Ulas, Brudvig, Shapiro (CR5) 2011; 5 Chertok, Moffat, David, Yu, Bergemann, Ross, Yang (CR6) 2008; 29 Yu, Falkner, Yavuz, Colvin (CR13) 2004; 0 Joshi, Lin, Aslam, Prasad, Schultz-Sikma, Edelman, Meade, Dravid (CR24) 2009; 113 Jiang, Yang, Yang, Horng, Hung, Chen, Hong (CR27) 2004; 283 Thorek, Tsourkas (CR10) 2008; 29 Kim, Kim, Lee (CR21) 2003; 337 Tanaka, Narita, Kitamura, Uchiyama, Morita, Inubushi, Chujo (CR3) 2010; 26 Lu, Salabas, Schuth (CR2) 2007; 46 Artan, Haider, Langer, van der Kwast, Evans, Yang, Wernick, Trachtenberg, Yetik (CR4) 2010; 19 Chouly, Pouliquen, Lucet, Jeune, Jallet (CR12) 1996; 13 Crosa, Boero, Angela (CR23) 1999; 47 Hasegawa, Saw (CR14) 1967; 38 Tromsdorf, Bigall, Kaul, Bruns, Nikolic, Mollwitz, Sperling, Reimer, Hohenberg, Parak, Forster, Beisiegel, Adam, Weller (CR9) 2007; 7 Ibrahim, Zhao, Seehra (CR22) 1992; 7 Shapiro, Skrtic, Sharer, Hill, Dunbar, Koretsky (CR26) 2004; 101 Yoon, Yu, Kim, Kim, Kim, Yun, Sohn, Cho, Lee, Park (CR19) 2006; 2 Laurent, Forge, Port, Roch, Robic, van der Elst, Muller (CR18) 2008; 108 Lee, Lee, Xu, Xie, Lee, Wu, Koh, Wang, Sinclair, Wang, Nishimura, Biswal, Sun, Cho, Chen (CR16) 2008; 19 Jun, Huh, Choi, Lee, Song, Kim, Yoon, Kim, Shin, Suh, Cheon (CR25) 2005; 127 WW Yu (1618_CR13) 2004; 0 NR Jana (1618_CR15) 2004; 16 HY Lee (1618_CR16) 2008; 19 Y Jun (1618_CR25) 2005; 127 UI Tromsdorf (1618_CR9) 2007; 7 B Chertok (1618_CR6) 2008; 29 S Laurent (1618_CR18) 2008; 108 M Crosa (1618_CR23) 1999; 47 L Matuszewski (1618_CR11) 2005; 235 W Jiang (1618_CR27) 2004; 283 DL Thorek (1618_CR10) 2008; 29 SJ Lee (1618_CR20) 2004; 282 C Chouly (1618_CR12) 1996; 13 MF Bennewitz (1618_CR5) 2011; 5 AH Lu (1618_CR2) 2007; 46 RT Branca (1618_CR7) 2010; 107 YI Kim (1618_CR21) 2003; 337 F Sonvico (1618_CR8) 2005; 16 KR Hasegawa (1618_CR14) 1967; 38 MM Ibrahim (1618_CR22) 1992; 7 K Tanaka (1618_CR3) 2010; 26 WJ Mulder (1618_CR17) 2006; 19 TJ Yoon (1618_CR19) 2006; 2 HM Joshi (1618_CR24) 2009; 113 EM Shapiro (1618_CR26) 2004; 101 MS Judenhofer (1618_CR1) 2008; 14 Y Artan (1618_CR4) 2010; 19 17193022 - Small. 2006 Feb;2(2):209-15 15749976 - Radiology. 2005 Apr;235(1):155-61 8860681 - J Microencapsul. 1996 May-Jun;13(3):245-55 18376410 - Nat Med. 2008 Apr;14 (4):459-65 18543879 - Chem Rev. 2008 Jun;108(6):2064-110 21394237 - Nanotechnology. 2008 Apr;19(16):165101 20716496 - IEEE Trans Image Process. 2010 Sep;19(9):2444-55 20527913 - Langmuir. 2010 Jul 20;26(14):11759-62 15839639 - J Am Chem Soc. 2005 Apr 27;127(16):5732-3 15256592 - Proc Natl Acad Sci U S A. 2004 Jul 27;101(30):10901-6 18533252 - Biomaterials. 2008 Sep;29(26):3583-90 16173796 - Bioconjug Chem. 2005 Sep-Oct;16(5):1181-8 20142483 - Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3693-7 17278160 - Angew Chem Int Ed Engl. 2007;46(8):1222-44 16450332 - NMR Biomed. 2006 Feb;19(1):142-64 21850276 - J Phys Chem C Nanomater Interfaces. 2009;113(41):17761-17767 17964647 - Biomaterials. 2008 Feb;29(4):487-96 17658761 - Nano Lett. 2007 Aug;7(8):2422-7 21495676 - ACS Nano. 2011 May 24;5(5):3438-46 15489993 - Chem Commun (Camb). 2004 Oct 21;(20):2306-7 |
| References_xml | – volume: 46 start-page: 1222 year: 2007 end-page: 1244 ident: CR2 article-title: Magnetic nanoparticles: synthesis, protection, functionalization, and application publication-title: Angew Chem Int Ed Engl doi: 10.1002/anie.200602866 – volume: 7 start-page: 1856 year: 1992 end-page: 1860 ident: CR22 article-title: Determination of particle size distribution in an Fe O -based catalyst using magnetometry and X-ray diffraction publication-title: J Mater Res doi: 10.1557/JMR.1992.1856 – volume: 14 start-page: 459 year: 2008 end-page: 465 ident: CR1 article-title: Simultaneous PET-MRI: a new approach for functional and morphological imaging publication-title: Nat Med doi: 10.1038/nm1700 – volume: 127 start-page: 5732 year: 2005 end-page: 5733 ident: CR25 article-title: Nanoscale size effect of magnetic nanocrystals and their utilization for cancer diagnosis via magnetic resonance imaging publication-title: J Am Chem Soc doi: 10.1021/ja0422155 – volume: 47 start-page: 742 year: 1999 end-page: 747 ident: CR23 article-title: Determination of mean crystallite dimensions from X-ray diffraction peak profiles: a comparative analysis of synthetic hematites publication-title: Clays Clay Miner doi: 10.1346/CCMN.1999.0470608 – volume: 101 start-page: 10901 year: 2004 end-page: 10906 ident: CR26 article-title: MRI detection of single particles for cellular imaging publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.0403918101 – volume: 16 start-page: 3931 year: 2004 end-page: 3935 ident: CR15 article-title: Size- and shape-controlled magnetic (Cr, Mn, Fe, Co, Ni) oxide nanocrystals via a simple and general approach publication-title: Chem Mater doi: 10.1021/cm049221k – volume: 282 start-page: 147 year: 2004 end-page: 150 ident: CR20 article-title: Synthesis and characterization of superparamagnetic maghemite nanoparticles prepared by coprecipitation technique publication-title: J Magn Magn Mater doi: 10.1016/j.jmmm.2004.04.035 – volume: 0 start-page: 2306 year: 2004 end-page: 2307 ident: CR13 article-title: Synthesis of monodisperse iron oxide nanocrystals by thermal decomposition of iron carboxylate salts publication-title: Chem Commun doi: 10.1039/b409601k – volume: 283 start-page: 210 year: 2004 end-page: 214 ident: CR27 article-title: Preparation and properties of superparamagnetic nanoparticles with narrow size distribution and biocompatible publication-title: J Magn Magn Mater doi: 10.1016/j.jmmm.2004.05.022 – volume: 108 start-page: 2064 year: 2008 end-page: 2110 ident: CR18 article-title: Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications publication-title: Chem Rev doi: 10.1021/cr068445e – volume: 19 start-page: 2444 year: 2010 end-page: 2455 ident: CR4 article-title: Prostate cancer localization with multispectral MRI using cost-sensitive support vector machines and conditional random fields publication-title: IEEE Trans Image Process doi: 10.1109/TIP.2010.2048612 – volume: 26 start-page: 11759 year: 2010 end-page: 11762 ident: CR3 article-title: Preparation for highly sensitive MRI contrast agents using core/shell type nanoparticles consisting of multiple SPIO cores with thin silica coating publication-title: Langmuir doi: 10.1021/la1015077 – volume: 29 start-page: 487 year: 2008 end-page: 496 ident: CR6 article-title: Iron oxide nanoparticles as a drug delivery vehicle for MRI monitored magnetic targeting of brain tumors publication-title: Biomaterials doi: 10.1016/j.biomaterials.2007.08.050 – volume: 5 start-page: 3438 year: 2011 end-page: 3446 ident: CR5 article-title: Biocompatible and pH-sensitive PLGA encapsulated MnO nanocrystals for molecular and cellular MRI publication-title: ACS Nano doi: 10.1021/nn1019779 – volume: 337 start-page: 42 year: 2003 end-page: 53 ident: CR21 article-title: Synthesis and characterization of CoFe O4 magnetic nanoparticles prepared by temperature-controlled coprecipitation method publication-title: Physica B doi: 10.1016/S0921-4526(03)00322-3 – volume: 113 start-page: 17761 year: 2009 end-page: 17767 ident: CR24 article-title: Effects of shape and size of cobalt ferrite nanostructures on their MRI contrast and thermal activation publication-title: J Phys Chem C doi: 10.1021/jp905776g – volume: 2 start-page: 209 year: 2006 end-page: 215 ident: CR19 article-title: Specific targeting, cell sorting, and bioimaging with smart magnetic silica core-shell nanomaterials publication-title: Small doi: 10.1002/smll.200500360 – volume: 7 start-page: 2422 year: 2007 end-page: 2427 ident: CR9 article-title: Size and surface effects on the MRI relaxivity of manganese ferrite nanoparticle contrast agents publication-title: Nano Lett doi: 10.1021/nl071099b – volume: 29 start-page: 3583 year: 2008 end-page: 3590 ident: CR10 article-title: Size, charge and concentration dependent uptake of iron oxide particles by non-phagocytic cells publication-title: Biomaterials doi: 10.1016/j.biomaterials.2008.05.015 – volume: 235 start-page: 155 year: 2005 end-page: 161 ident: CR11 article-title: Cell tagging with clinically approved iron oxides: feasibility and effect of lipofection, particle size, and surface coating on labeling efficiency publication-title: Radiology doi: 10.1148/radiol.2351040094 – volume: 13 start-page: 245 year: 1996 end-page: 255 ident: CR12 article-title: Development of superparamagnetic nanoparticles for MRI: effect of particle size, charge and surface nature on biodistribution publication-title: J Microencapsul doi: 10.3109/02652049609026013 – volume: 16 start-page: 1181 year: 2005 end-page: 1188 ident: CR8 article-title: Folate-conjugated iron oxide nanoparticles for solid tumor targeting as potential specific magnetic hyperthermia mediators: synthesis, physicochemical characterization, and experiments publication-title: Bioconjug Chem doi: 10.1021/bc050050z – volume: 38 start-page: 4707 year: 1967 end-page: 4712 ident: CR14 article-title: Particle-size distribution of CoFe O formed by the coprecipitation method publication-title: J Appl Phys doi: 10.1063/1.1709207 – volume: 19 start-page: 142 year: 2006 end-page: 164 ident: CR17 article-title: Lipid-based nanoparticles for contrast-enhanced MRI and molecular imaging publication-title: NMR Biomed doi: 10.1002/nbm.1011 – volume: 19 start-page: 165101 year: 2008 end-page: 165106 ident: CR16 article-title: Synthesis and characterization of PVP-coated large core iron oxide nanoparticles as an MRI contrast agent publication-title: Nanotechnology doi: 10.1088/0957-4484/19/16/165101 – volume: 107 start-page: 3693 year: 2010 end-page: 3697 ident: CR7 article-title: Molecular MRI for sensitive and specific detection of lung metastases publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.1000386107 – volume: 19 start-page: 165101 year: 2008 ident: 1618_CR16 publication-title: Nanotechnology doi: 10.1088/0957-4484/19/16/165101 – volume: 29 start-page: 487 year: 2008 ident: 1618_CR6 publication-title: Biomaterials doi: 10.1016/j.biomaterials.2007.08.050 – volume: 16 start-page: 1181 year: 2005 ident: 1618_CR8 publication-title: Bioconjug Chem doi: 10.1021/bc050050z – volume: 38 start-page: 4707 year: 1967 ident: 1618_CR14 publication-title: J Appl Phys doi: 10.1063/1.1709207 – volume: 19 start-page: 142 year: 2006 ident: 1618_CR17 publication-title: NMR Biomed doi: 10.1002/nbm.1011 – volume: 127 start-page: 5732 year: 2005 ident: 1618_CR25 publication-title: J Am Chem Soc doi: 10.1021/ja0422155 – volume: 107 start-page: 3693 year: 2010 ident: 1618_CR7 publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.1000386107 – volume: 26 start-page: 11759 year: 2010 ident: 1618_CR3 publication-title: Langmuir doi: 10.1021/la1015077 – volume: 16 start-page: 3931 year: 2004 ident: 1618_CR15 publication-title: Chem Mater doi: 10.1021/cm049221k – volume: 19 start-page: 2444 year: 2010 ident: 1618_CR4 publication-title: IEEE Trans Image Process doi: 10.1109/TIP.2010.2048612 – volume: 0 start-page: 2306 year: 2004 ident: 1618_CR13 publication-title: Chem Commun doi: 10.1039/b409601k – volume: 14 start-page: 459 year: 2008 ident: 1618_CR1 publication-title: Nat Med doi: 10.1038/nm1700 – volume: 2 start-page: 209 year: 2006 ident: 1618_CR19 publication-title: Small doi: 10.1002/smll.200500360 – volume: 7 start-page: 1856 year: 1992 ident: 1618_CR22 publication-title: J Mater Res doi: 10.1557/JMR.1992.1856 – volume: 47 start-page: 742 year: 1999 ident: 1618_CR23 publication-title: Clays Clay Miner doi: 10.1346/CCMN.1999.0470608 – volume: 282 start-page: 147 year: 2004 ident: 1618_CR20 publication-title: J Magn Magn Mater doi: 10.1016/j.jmmm.2004.04.035 – volume: 13 start-page: 245 year: 1996 ident: 1618_CR12 publication-title: J Microencapsul doi: 10.3109/02652049609026013 – volume: 337 start-page: 42 year: 2003 ident: 1618_CR21 publication-title: Physica B doi: 10.1016/S0921-4526(03)00322-3 – volume: 113 start-page: 17761 year: 2009 ident: 1618_CR24 publication-title: J Phys Chem C doi: 10.1021/jp905776g – volume: 235 start-page: 155 year: 2005 ident: 1618_CR11 publication-title: Radiology doi: 10.1148/radiol.2351040094 – volume: 7 start-page: 2422 year: 2007 ident: 1618_CR9 publication-title: Nano Lett doi: 10.1021/nl071099b – volume: 46 start-page: 1222 year: 2007 ident: 1618_CR2 publication-title: Angew Chem Int Ed Engl doi: 10.1002/anie.200602866 – volume: 5 start-page: 3438 year: 2011 ident: 1618_CR5 publication-title: ACS Nano doi: 10.1021/nn1019779 – volume: 101 start-page: 10901 year: 2004 ident: 1618_CR26 publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.0403918101 – volume: 108 start-page: 2064 year: 2008 ident: 1618_CR18 publication-title: Chem Rev doi: 10.1021/cr068445e – volume: 283 start-page: 210 year: 2004 ident: 1618_CR27 publication-title: J Magn Magn Mater doi: 10.1016/j.jmmm.2004.05.022 – volume: 29 start-page: 3583 year: 2008 ident: 1618_CR10 publication-title: Biomaterials doi: 10.1016/j.biomaterials.2008.05.015 – reference: 18543879 - Chem Rev. 2008 Jun;108(6):2064-110 – reference: 15839639 - J Am Chem Soc. 2005 Apr 27;127(16):5732-3 – reference: 15256592 - Proc Natl Acad Sci U S A. 2004 Jul 27;101(30):10901-6 – reference: 20716496 - IEEE Trans Image Process. 2010 Sep;19(9):2444-55 – reference: 21495676 - ACS Nano. 2011 May 24;5(5):3438-46 – reference: 20527913 - Langmuir. 2010 Jul 20;26(14):11759-62 – reference: 17278160 - Angew Chem Int Ed Engl. 2007;46(8):1222-44 – reference: 16173796 - Bioconjug Chem. 2005 Sep-Oct;16(5):1181-8 – reference: 8860681 - J Microencapsul. 1996 May-Jun;13(3):245-55 – reference: 21850276 - J Phys Chem C Nanomater Interfaces. 2009;113(41):17761-17767 – reference: 16450332 - NMR Biomed. 2006 Feb;19(1):142-64 – reference: 17964647 - Biomaterials. 2008 Feb;29(4):487-96 – reference: 17193022 - Small. 2006 Feb;2(2):209-15 – reference: 15749976 - Radiology. 2005 Apr;235(1):155-61 – reference: 18376410 - Nat Med. 2008 Apr;14 (4):459-65 – reference: 20142483 - Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3693-7 – reference: 15489993 - Chem Commun (Camb). 2004 Oct 21;(20):2306-7 – reference: 21394237 - Nanotechnology. 2008 Apr;19(16):165101 – reference: 17658761 - Nano Lett. 2007 Aug;7(8):2422-7 – reference: 18533252 - Biomaterials. 2008 Sep;29(26):3583-90 |
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| Title | Size-regulated group separation of CoFe2O4 nanoparticles using centrifuge and their magnetic resonance contrast properties |
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