Antigen presentation by dendritic cells in rheumatoid arthritis

• Published in: Current topics in medicinal chemistry Vol. 13; no. 6; p. 712
• Main Author: Rodríguez-Fernández, José Luis
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 2013
• Subjects: Animals; Antigen Presentation - immunology; Arthritis, Rheumatoid - immunology; Dendritic Cells - immunology; Humans

Rheumatoid Arthritis (RA) is a chronic autoimmune inflammatory disease that affects largely synovial joints. It has been postulated that activated autoreactive CD4 T cells play a key role in triggering and/or maintaining the chronic inflammatory process in RA. Dendritic cells (DCs) are antigen-prese...