Association between high-sensitivity C-reactive protein and bleeding in dual antiplatelet therapy age: a retrospective observational study

• Published in: BMJ open Vol. 15; no. 2; p. e082900
• Main Authors: He, Wen-fei, Zeng, Li-huan, Lin, Zi-jing, Chen, Peng-yuan, Liu, Yuan-hui, Duan, Chongyang, Jiang, Lei, Guo, Zhi-qiang, He, Peng-cheng
• Format: Journal Article
• Language: English
• Published: England British Medical Journal Publishing Group 12.02.2025; BMJ Publishing Group LTD; BMJ Publishing Group
• Subjects: Acute Coronary Syndrome - blood; Acute Coronary Syndrome - drug therapy; Acute coronary syndromes; Aged; Anemia; Angina pectoris; Biomarkers - blood; Bleeding disorders & coagulopathies; C-reactive protein; C-Reactive Protein - analysis; C-Reactive Protein - metabolism; Cardiac arrhythmia; Cardiovascular Disease; Cardiovascular Medicine; China - epidemiology; Clinical outcomes; Coronary heart disease; Coronary vessels; Diabetes; Dual Anti-Platelet Therapy - adverse effects; Female; Heart attacks; Hemoglobin; Hemorrhage - blood; Hemorrhage - chemically induced; Hemorrhage - epidemiology; Humans; Hypertension; Inflammation; Ischemia; Male; Middle Aged; Myocardial infarction; Observational studies; Original Research; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors - adverse effects; Platelet Aggregation Inhibitors - therapeutic use; Proteins; Retrospective Studies; Risk Factors; Statistical analysis; Stroke; Trends; Variables; China; Cardiovascular Disease; Myocardial infarction; Coronary heart disease; Risk Factors; Bleeding disorders & coagulopathies

ObjectivesThe aim of the present study was to investigate the association of high-sensitivity C-reactive protein (hs-CRP) with bleeding events among patients with acute coronary syndrome (ACS) received dual antiplatelet therapy (DAPT) after percutaneous coronary intervention.DesignAn observational a...