Evaluation of the effectiveness and safety of a novel substrate-based radiofrequency ablation for persistent atrial fibrillation: a prospective, randomised, parallel-controlled, single-blinded study protocol

• Published in: BMJ open Vol. 14; no. 2; p. e080539
• Main Authors: Yang, Jie, Song, Yuanbin, Bian, Shizhu, Zhang, Bo, Zhang, Yi, Wang, Xia, Cheng, Li, Fan, Yu, Liu, Changsong, Tan, Hu
• Format: Journal Article
• Language: English
• Published: England British Medical Journal Publishing Group 27.02.2024; BMJ Publishing Group LTD; BMJ Publishing Group
• Series: Protocol
• Subjects: Ablation; Antiarrhythmics; Atrial Fibrillation - etiology; Cardiac arrhythmia; cardiology; Cardiovascular disease; Cardiovascular Medicine; Catheter Ablation - methods; Catheters; Chronic obstructive pulmonary disease; coronary intervention; Coronary vessels; Heart Atria; Hospitals; Humans; interventional radiology; Patients; Prospective Studies; Pulmonary Veins - surgery; randomized controlled trial; Randomized Controlled Trials as Topic; Recurrence; Sinuses; Treatment Outcome; Vein & artery diseases; coronary intervention; cardiovascular disease; interventional radiology; cardiology; randomized controlled trial

IntroductionPulmonary vein isolation (PVI) is the cornerstone of radiofrequency (RF) ablation for atrial fibrillation (AF). However, a single ablation strategy does not always achieve the desired therapeutic effect in all patients with persistent AF, and individualised strategies are required for di...