Generation and characterization of human Fetal membrane and Decidual cell lines for reproductive biology experiments

• Published in: Biology of reproduction Vol. 106; no. 3; pp. 568 - 582
• Main Authors: Radnaa, Enkhtuya, Urrabaz-Garza, Rheanna, Elrod, Nathan D., de Castro Silva, Mariana, Pyles, Richard, Han, Arum, Menon, Ramkumar
• Format: Journal Article
• Language: English
• Published: United States Society for the Study of Reproduction 19.03.2022; Oxford University Press
• Subjects: Amnion; Biology; Cell activation; Cell Line; Cell lines; Cell morphology; Chorion; Cytology; Decidua; Decidua - metabolism; Deoxyribonucleic acid; DNA; Epithelial cells; Extraembryonic Membranes - metabolism; Female; fetal-maternal cells; Fetuses; Gene expression; Genetic drift; HPV16E6E7; Human placental fetal membrane; Humans; Interfaces; Mesenchyme; Morphology; Physical characteristics; Placenta; Placenta - metabolism; Pregnancy; RESEARCH ARTICLE; Short tandem repeats; Signal transduction; SV40T-based immortalization; fetal-maternal cells; Human placental fetal membrane; SV40T-based immortalization; HPV16E6E7

Human fetal membrane and maternal decidua parietalis form one of the major feto-maternal interfaces during pregnancy. Studies on this feto-maternal interface is limited as several investigators have limited access to the placenta, and experience difficulties to isolate and maintain primary cells. Ma...