Persistently high venous-to-arterial carbon dioxide differences during early resuscitation are associated with poor outcomes in septic shock

• Published in: Critical care (London, England) Vol. 17; no. 6; p. R294
• Main Authors: Ospina-Tascón, Gustavo A, Bautista-Rincón, Diego F, Umaña, Mauricio, Tafur, José D, Gutiérrez, Alejandro, García, Alberto F, Bermúdez, William, Granados, Marcela, Arango-Dávila, César, Hernández, Glenn
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 13.12.2013; BioMed Central
• Subjects: Aged; Blood flow; Carbon dioxide; Carbon Dioxide - blood; Cardiac Output; Complications and side effects; Female; Hemodynamics; Humans; Lactic Acid - blood; Male; Middle Aged; Multiple Organ Failure - etiology; Oxygen - blood; Oxygen Consumption; Physiological aspects; Prognosis; Prospective Studies; Septic shock; Shock, Septic - blood; Shock, Septic - complications; Shock, Septic - mortality; Shock, Septic - therapy; Survival Analysis; United States

Venous-to-arterial carbon dioxide difference (Pv-aCO2) may reflect the adequacy of blood flow during shock states. We sought to test whether the development of Pv-aCO2 during the very early phases of resuscitation is related to multi-organ dysfunction and outcomes in a population of septic shock pat...