Helicobacter pylori related hypergastrinaemia is the result of a selective increase in gastrin 17

• Published in: Gut Vol. 34; no. 6; pp. 757 - 761
• Main Authors: Mulholland, G, Ardill, J E, Fillmore, D, Chittajallu, R S, Fullarton, G M, McColl, K E
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and British Society of Gastroenterology 01.06.1993; BMJ; BMJ Publishing Group LTD
• Subjects: Adult; Bacterial diseases; Bacterial diseases of the digestive system and abdomen; Biological and medical sciences; Duodenal Ulcer - blood; Eating - physiology; Female; Gastrins - blood; Helicobacter Infections - blood; Helicobacter pylori; Human bacterial diseases; Humans; Infectious diseases; Male; Medical sciences; Middle Aged; Protein Precursors - blood; Human; Assay; Gastrointestinal hormone; Spirillales; Helicobacter pylori; Postprandial; Gastrin; Spirillaceae; Bacteria; Chromatography; Comparative study; Hypergastrinemia

Helicobacter pylori infection increases the serum concentration of gastrin, and this may be one of the mechanisms by which it predisposes to duodenal ulceration. Different forms of circulating gastrin were studied both basally and postprandially in 13 duodenal ulcer patients before and one month aft...