Effects of hemodilution on coagulation function during prolonged hypotensive resuscitation in a porcine model of severe hemorrhagic shock

• Published in: Trauma surgery & acute care open Vol. 8; no. 1; p. e001052
• Main Authors: Neidert, Leslie E, Morgan, Clifford G, Hathaway, Emily N, Hemond, Peter J, Tiller, Michael M, Cardin, Sylvain, Glaser, Jacob J
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group Ltd 16.05.2023; BMJ Publishing Group LTD; BMJ Publishing Group
• Subjects: Anticoagulants; Blood & organ donations; Blood coagulation; Blood pressure; Blood products; Clinical medicine; Clinical practice guidelines; Euthanasia; Hemorrhage; Hemorrhagic shock; Hospitalization; Hypotension; Injuries; Laboratory animals; Original Research; resuscitation; Shock, Hemorrhagic; Trauma; Blood coagulation; resuscitation; Shock, Hemorrhagic

BackgroundAlthough hemorrhage remains the leading cause of survivable death in casualties, modern conflicts are becoming more austere limiting available resources to include resuscitation products. With limited resources also comes prolonged evacuation time, leaving suboptimal prehospital field care...