Gonadotropin-inhibitory hormone in Gambel's white-crowned sparrow (Zonotrichia leucophrys gambelii): cDNA identification, transcript localization and functional effects in laboratory and field experiments

• Published in: Journal of endocrinology Vol. 182; no. 1; pp. 33 - 42
• Main Authors: Osugi, T, Ukena, K, Bentley, GE, O'Brien, S, Moore, IT, Wingfield, JC, Tsutsui, K
• Format: Journal Article
• Language: English
• Published: Colchester BioScientifica 01.07.2004; Portland Press
• Subjects: Animals; Avian Proteins - genetics; Avian Proteins - metabolism; Base Sequence; Biological and medical sciences; Birds - metabolism; Brain - metabolism; Chickens; Coturnix; DNA, Complementary - analysis; Fundamental and applied biological sciences. Psychology; Hormones and neuropeptides. Regulation; Hypothalamus. Hypophysis. Epiphysis. Urophysis; Immunohistochemistry - methods; In Situ Hybridization - methods; Luteinizing Hormone - blood; Male; Molecular Sequence Data; Orchiectomy; Peptide Hormones - genetics; Peptide Hormones - metabolism; Quail; Recombinant Proteins - pharmacology; Sequence Alignment; Vertebrates: endocrinology; Zonotrichia leucophrys; Central nervous system; Gonadotropin RH; Gonadotropin; Hypothalamus; Paraventricular nucleus; Coturnix japonica; Encephalon; Hypothalamic hormone; Gonadotropin IH; Vertebrata; Adenohypophyseal hormone; Adult animal; Hormonal regulation; Luteinizing hormone; Aves; Hormone releasing factor; Molecular cloning; Localization; Comparative study

The neuropeptide control of gonadotropin secretion is primarily through the stimulatory action of the hypothalamic decapeptide, GnRH. We recently identified a novel hypothalamic dodecapeptide with a C-terminal LeuPro-Leu-Arg-Phe-NH2 sequence in the domestic bird, Japanese quail (Coturnix japonica)....