Labdanes of Natural Origin-Biological Activities (1981-2004)

• Published in: Current medicinal chemistry Vol. 12; no. 11; pp. 1295 - 1317
• Main Author: CHINOU, I
• Format: Journal Article
• Language: English
• Published: Schiphol Bentham Science Publishers Ltd 01.01.2005; Bentham Science
• Subjects: Animals; Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - pharmacology; Biological and medical sciences; Biological Factors - chemistry; Biological Factors - isolation & purification; Biological Factors - pharmacology; Carbohydrates - chemistry; Carbohydrates - pharmacology; Enzyme Inhibitors - chemistry; Enzyme Inhibitors - pharmacology; Humans; Medical sciences; Miscellaneous; Pharmacology. Drug treatments; Superoxides - antagonists & inhibitors; Superoxides - metabolism; Terpenes - chemistry; Terpenes - classification; Terpenes - isolation & purification; Terpenes - pharmacology; Terpenoid; Pharmacognosy; Animal origin; Biosynthesis; Case history; Biological activity; Medicinal plant; Marine environment; plant families; Labdane-type diterpenes; Plant origin; Diterpene; Labdane derivatives; bioactivities
• ISSN: 0929-8673; 1875-533X
• DOI: 10.2174/0929867054020990

Terpenoids is a class of natural compounds found in higher plants, mosses, liverworts, algae and lichens, as well as in insects, microbes or marine organisms. Through centuries many of these compounds have been used as ingredients of perfumes, drugs, narcotics or pigments. Labdanes, belonging to the bicyclic diterpenoids group, have been found as secondary metabolites in tissues of fungi, insects, marine organisms, and in essential oils, resins and tissues of higher plants. The diterpenes of labdane type, have been reported to have broad spectrum of biological activities. In this study, the reported bioactivities and/or uses of them, the last two decades (1981-2004), are selected as an attempt to underline their role in nature.