Surface marker and other characteristics of Gaucher's cells

A full surface marker study of the splenic storage cells in a case of Gaucher's disease largely substantiates the monocyte/histiocyte nature of Gaucher's cells. In addition, an apparent T-lymphocyte deficiency is demonstrated in the spleen and peripheral blood, and the possible significanc...

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Bibliographic Details
Published inJournal of clinical pathology Vol. 30; no. 10; pp. 981 - 988
Main Authors Burns, G F, Cawley, J C, Flemans, R J, Higgy, K E, Worman, C P, Barker, C R, Roberts, B E, Hayhoe, F G
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group Ltd and Association of Clinical Pathologists 01.10.1977
BMJ Publishing Group LTD
Subjects
Cell Extracts - immunology
Child
Female
Gaucher Disease - immunology
Gaucher Disease - pathology
Humans
Leukocyte Count
Receptors, Antigen, B-Cell - analysis
Rosette Formation
Spleen - immunology
Spleen - ultrastructure
T-Lymphocytes - immunology
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Summary:A full surface marker study of the splenic storage cells in a case of Gaucher's disease largely substantiates the monocyte/histiocyte nature of Gaucher's cells. In addition, an apparent T-lymphocyte deficiency is demonstrated in the spleen and peripheral blood, and the possible significance of this finding is discussed.
Bibliography:ark:/67375/NVC-V1F65M97-9
local:jclinpath;30/10/981
PMID:304070
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href:jclinpath-30-981.pdf
ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:0021-9746
1472-4146
DOI:10.1136/jcp.30.10.981