The Interrelationship between HIV Infection and COVID-19: A Review of the Literature

• Published in: Current HIV research Vol. 22; no. 1; p. 6
• Main Authors: Wang, Yiyu, Lai, Yu
• Format: Journal Article
• Language: English
• Published: Netherlands 2024
• Subjects: Coinfection - epidemiology; Coinfection - virology; COVID-19 - complications; COVID-19 - epidemiology; COVID-19 Vaccines; HIV Infections - complications; HIV Infections - epidemiology; Humans; SARS-CoV-2; SARS-CoV-2; Coinfection; HIV; epidemic; Keywords: COVID-19; PLWH; virus
• ISSN: 1873-4251
• DOI: 10.2174/011570162X282739231222062830

The Corona Virus Disease 2019 (COVID-19) pandemic resulting from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to significant morbidity and mortality in patients and put a strain on healthcare systems worldwide. The clinical characteristics and results of COVID-19 in immunosuppressed patients, such as people living with human immunodeficiency virus (PLWH), considered at higher risk of severe disease, are not well-characterized. Accumulated evidence indicates that COVID-19 and the human immunodeficiency virus (HIV) can interact in various ways. This review explored the similarities and differences in virology between SARS-CoV-2 and HIV, the effect of the COVID-19 vaccine on PLWH, the impact of the COVID-19 pandemic on PLWH care and prevention, and the influence of HIV-related factors on COVID-19. Discovering the potential link between HIV and COVID-19 may provide a novel way to avoid the factors of HIV and SARS-CoV-2 co-infection and advance future research.