Astragaloside IV regulates insulin resistance and inflammatory response of adipocytes via modulating miR-21/PTEN/PI3K/AKT signaling

• Published in: Endocrine, metabolic & immune disorders drug targets
• Main Authors: Guo, Xuxi, Yin, Taoqing, Chen, Dongni, Xu, Shuai, Ye, Renqun, Zhang, Yue
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01.01.2023
• Subjects: T2DM; AS-IV; miR-21; inflammation; adipocytes; insulin resistance

Background The progression of Type 2 Diabetes Mellitus (T2DM) can lead to various complications. Compounds derived from natural products have been found to be effective in combatting T2DM. This study aimed to investigate the effects of Astragaloside IV (AS-IV) on insulin resistance and the inflammat...