Can microstructural MRI detect subclinical tissue injury in subjects with asymptomatic cervical spinal cord compression? A prospective cohort study

• Published in: BMJ open Vol. 8; no. 4; p. e019809
• Main Authors: Martin, Allan R, De Leener, Benjamin, Cohen-Adad, Julien, Cadotte, David W, Nouri, Aria, Wilson, Jefferson R, Tetreault, Lindsay, Crawley, Adrian P, Mikulis, David J, Ginsberg, Howard, Fehlings, Michael G
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group LTD 01.04.2018; BMJ Publishing Group
• Subjects: Ataxia; Automation; Cohort analysis; Gait; Magnetic resonance imaging; Measurement techniques; Neurology; NMR; Nuclear magnetic resonance; Principal components analysis; Spinal cord; spinal cord injury; diffusion tensor imaging; magnetization transfer; preclinical; myelopathy; quantitative mri

ObjectivesDegenerative cervical myelopathy (DCM) involves extrinsic spinal cord compression causing tissue injury and neurological dysfunction. Asymptomatic spinal cord compression (ASCC) is more common, but its significance is poorly defined. This study investigates if: (1) ASCC can be automaticall...