The COMET (Comparison of Operative versus Monitoring and Endocrine Therapy) trial: a phase III randomised controlled clinical trial for low-risk ductal carcinoma in situ (DCIS) - Hwang, E Shelley; Hyslop, Terry; Lynch, Thomas; Frank, Elizabeth; Pinto, Donna; Basila, Desiree; Collyar, Deborah; Bennett, Antonia; Kaplan, Celia; Rosenberg, Shoshana; Thompson, Alastair; Weiss, Anna; et al. (BMJ open, 2019)
Keywords: Breast cancer; Breast Neoplasms - prevention & control; Breast Neoplasms - therapy; Cancer surgery; Cancer therapies; Carcinoma in Situ - pathology; Carcinoma in Situ - therapy; Carcinoma, Ductal, Breast - pathology; Carcinoma, Ductal, Breast - therapy; Clinical trials; Combined Modality Therapy; Endocrine therapy; Evidence-based medicine; Female; Humans; Mammography; Mastectomy; Middle Aged; Pain; Patient Outcome Assessment; Patient-Centred Medicine; Patients; Prostate cancer; Risk Assessment; Surveillance; Watchful Waiting; Womens health; United Kingdom--UK; United States--US; clinical trial; ductal carcinoma in situ; breast cancer; non-invasive; active surveillance; surgery