The impact of lncRNA-GAS5/miRNA-200/ACE2 molecular pathway on the severity of COVID-19

• Published in: Current medicinal chemistry
• Main Authors: Ayeldeen, Ghada, Shaker, Olfat G, Amer, Eman, Zaafan, Mai A, Herzalla, Mohamed R, Keshk, Mofida A, Abdelhamid, Amr M
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01.01.2024
• Subjects: ACE2; COVID-19 comorbidities; Lnc-GAS5; COVID-19 patients; COVID-19 severity; miRNA-200

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is responsible for coronavirus disease (COVID-19), potentially has severe adverse effects, leading to public health crises worldwide. In COVID-19, deficiency of ACE-2 is linked to increased inflammation and cytokine storms via i...