Hypogonadism as a risk factor for cardiovascular mortality in men: a meta-analytic study

• Published in: European journal of endocrinology Vol. 165; no. 5; pp. 687 - 701
• Main Authors: Corona, Giovanni, Rastrelli, Giulia, Monami, Matteo, Guay, André, Buvat, Jaques, Sforza, Alessandra, Forti, Gianni, Mannucci, Edoardo, Maggi, Mario
• Format: Journal Article
• Language: English
• Published: Bristol BioScientifica 01.11.2011; European Society of Endocrinology
• Subjects: Animals; Biological and medical sciences; Cardiovascular Diseases - blood; Cardiovascular Diseases - mortality; Endocrinopathies; Estradiol - blood; Fundamental and applied biological sciences. Psychology; Humans; Hypogonadism - blood; Hypogonadism - mortality; Male; Medical sciences; Randomized Controlled Trials as Topic - methods; Review; Risk Factors; Testosterone - blood; Vertebrates: endocrinology; Human; Risk factor; Male; Cardiovascular disease; Endocrinology; Hypogonadism; Genital diseases; Metaanalysis

ObjectiveTo verify whether hypogonadism represents a risk factor for cardiovascular (CV) morbidity and mortality and to verify whether testosterone replacement therapy (TRT) improves CV parameters in subjects with known CV diseases (CVDs).DesignMeta-analysis.MethodsAn extensive Medline search was pe...