MTOR suppresses autophagy-mediated production of IL25 in allergic airway inflammation - Li, Wen; Wu, Yinfang; Zhao, Yun; Li, Zhouyang; Chen, Haixia; Dong, Lingling; Liu, Huiwen; Zhang, Min; Wu, Yanping; Zhou, Jiesen; Xiong, Juan; Hu, Yue; et al. (Thorax, 2020)
Keywords: Adult; Aged; airway epithelium; Airway management; Allergens; allergic lung disease; Animals; Asthma; Asthma - metabolism; Asthma - pathology; Asthma - physiopathology; asthma mechanisms; Autophagy; Autophagy - drug effects; Cells, Cultured; Cytokines; Epithelial Cells - metabolism; Experiments; Female; Gene Knockdown Techniques; Human subjects; Humans; Inflammation; Inflammation - metabolism; Inflammation - pathology; Interleukin-13 - metabolism; Interleukin-13 - pharmacology; Interleukin-17 - biosynthesis; Interleukin-33 - metabolism; Interleukin-33 - pharmacology; Interleukins - metabolism; Kinases; Laboratories; Male; Mice; Microscopy; Microtubule-Associated Proteins - genetics; Middle Aged; Pathogenesis; Proteins; Respiratory Mucosa - physiopathology; Signal Transduction; TOR Serine-Threonine Kinases - genetics; TOR Serine-Threonine Kinases - metabolism; Tuberous Sclerosis Complex 2 Protein - metabolism; United States--US; asthma mechanisms; asthma; allergic lung disease; airway epithelium