Biological agents for giant cell arteritis: treat to target

• Published in: Annals of the rheumatic diseases Vol. 75; no. 9; p. e58
• Main Authors: Moiseev, Sergey, Novikov, Pavel, Meshkov, Alexey, Smitienko, Ilya
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group LTD 01.09.2016
• Subjects: Biological products; Biopsy; Cardiovascular disease; Heart attacks; Immunotherapy; Medical prognosis; Mortality; Older people; Patients; Psoriasis; Rheumatology; Studies; DMARDs (biologic); Giant Cell Arteritis; Treatment; Systemic vasculitis

Another randomised, placebo-controlled trial ( NCT02531633 ) aims to study sirukumab (a fully human anti-IL-6 immunoglobulin G1[kappa]) in approximately 204 subjects with a diagnosis of GCA. [...]in the nearest future we will probably face a wider use of biological agents as a second-line treatment...