Comparison between deep brain stimulation and magnetic resonance-guided focused ultrasound in the treatment of essential tremor: a systematic review and pooled analysis of functional outcomes

• Published in: Journal of neurology, neurosurgery and psychiatry Vol. 91; no. 12; pp. 1270 - 1278
• Main Authors: Giordano, Martina, Caccavella, Valerio Maria, Zaed, Ismail, Foglia Manzillo, Livia, Montano, Nicola, Olivi, Alessandro, Polli, Filippo Maria
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group Ltd 01.12.2020; BMJ Publishing Group LTD
• Subjects: Activities of daily living; Bias; Deep brain stimulation; Deep Brain Stimulation - methods; Essential Tremor - physiopathology; Essential Tremor - therapy; Gait Disorders, Neurologic - epidemiology; Gait Disorders, Neurologic - physiopathology; High-Intensity Focused Ultrasound Ablation - methods; Humans; Hypesthesia - epidemiology; Hypesthesia - physiopathology; Implantable Neurostimulators; Magnetic Resonance Imaging; Movement disorders; Neurosurgical Procedures; Paresthesia - epidemiology; Paresthesia - physiopathology; Postoperative Complications - epidemiology; Postoperative Complications - physiopathology; Prosthesis Implantation; Quality of life; Speech Disorders - epidemiology; Speech Disorders - physiopathology; surgery; Surgery, Computer-Assisted; Systematic review; systematic reviews; Thalamus - surgery; Treatment Outcome; tremor; Tremor (Muscular contraction); Ultrasonic imaging; ultrasound; tremor; movement disorders; systematic reviews; ultrasound; surgery

The current gold standard surgical treatment for medication-resistant essential tremor (ET) is deep brain stimulation (DBS). However, recent advances in technologies have led to the development of incisionless techniques, such as magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy. The...