Integrative multiomics enhancer activity profiling identifies therapeutic vulnerabilities in cholangiocarcinoma of different etiologies - Hong, Jing Han; Yong, Chern Han; Heng, Hong Lee; Chan, Jason Yongsheng; Lau, Mai Chan; Chen, Jianfeng; Lee, Jing Yi; Lim, Abner Herbert; Li, Zhimei; Guan, Peiyong; Chu, Pek Lim; Boot, Arnoud; et al. (Gut, 2024)
Keywords: Animals; Aristolochic acid; Bile Duct Neoplasms - drug therapy; Bile Duct Neoplasms - genetics; Bile Duct Neoplasms - metabolism; Bile Duct Neoplasms - pathology; CANCER; Cancer therapies; Carcinogenesis; Cell Line, Tumor; Chemotherapy; CHOLANGIOCARCINOMA; Cholangiocarcinoma - drug therapy; Cholangiocarcinoma - genetics; Cholangiocarcinoma - metabolism; Cholangiocarcinoma - pathology; DNA methylation; Epigenetics; Estrogens; Etiology; Gene expression; Gene Expression Profiling - methods; Hepatology; Humans; Immunogenicity; Immunohistochemistry; Infections; Liver; Malignancy; Mice; MOLECULAR ONCOLOGY; Multiomics; Mutation; Oxidative phosphorylation; Phosphorylation; Population studies; Signal transduction; Therapeutic targets; TOR protein; Transcriptomics; Tumorigenesis; Tumors; CHOLANGIOCARCINOMA; CANCER; MOLECULAR ONCOLOGY